(Q28140623)

English

Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway

scientific article (publication date: 23 March 2001)

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scholarly article

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Activation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathway (English)

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author name string

B Souttou

1

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N B Carvalho

2

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D Raulais

3

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M Vigny

4

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language of work or name

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publication date

23 March 2001

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Journal of Biological Chemistry

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276

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12

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9526-31

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Signal transduction by receptors with tyrosine kinase activity

1 reference

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Protein modules and signalling networks

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Role of neurotrophic factors in neuronal development.

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Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain

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ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

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Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

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Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

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Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth

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Major nucleolar proteins shuttle between nucleus and cytoplasm

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region

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Beta PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells

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Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

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PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

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The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable

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EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

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PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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Insulin and insulin-like growth factors stimulate deoxyribonucleic acid synthesis in PC12 pheochromocytoma cells

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21 January 2018

Coupling of epidermal growth factor (EGF) with the antiproliferative activity of cAMP induces neuronal differentiation

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21 January 2018

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

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Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells

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10.1074/JBC.M007333200

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