(Q28141695)

1

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P Thomas

2

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J W Neal

3

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V J Weston

4

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P S Harper

6

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A L Jones

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

7

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language of work or name

English

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publication date

September 1999

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published in

Human Molecular Genetics

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volume

8

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issue

9

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page(s)

1647-55

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

A cellular model that recapitulates major pathogenic steps of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Regional and cellular expression of the Machado-Joseph disease gene in brains of normal and affected individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Androgen receptor and mechanism of androgen action

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Ataxin-3 is transported into the nucleus and associates with the nuclear matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Heterogeneous intracellular localization and expression of ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

A huntingtin-associated protein enriched in brain with implications for pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Molecular cloning of a protein kinase whose phosphorylation is regulated by genetic adhesion during Chlamydomonas fertilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin interacts with cystathionine beta-synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Huntingtin interacts with a family of WW domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Histone deacetylase activity is required for full transcriptional repression by mSin3A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Signal-specific co-activator domain requirements for Pit-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

What's up and down with histone deacetylation and transcription?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Fast transport and retrograde movement of huntingtin and HAP 1 in axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647

Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2F8.9.1647