(Q28142108)

English

Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1

scientific article (publication date: 30 April 1999)

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scholarly article

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Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1 (English)

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Human T-lymphotropic virus 1

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author name string

S G Blumenthal

1

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G Aichele

2

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T Wirth

3

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A P Czernilofsky

4

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A Nordheim

5

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J Dittmer

6

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language of work or name

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publication date

30 April 1999

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Journal of Biological Chemistry

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274

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18

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12910-6

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Characterization of the human interleukin-5 gene promoter: involvement of octamer binding sites in the gene promoter activity

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T-cell subsets: transcriptional control in the Th1/Th2 decision

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Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins

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Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein, and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells

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Identification of transcription factor binding sites important in the regulation of the human interleukin-5 gene

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Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

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Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome

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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

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Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation

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Kinetic analysis of human T-cell leukemia virus type I Tax-mediated activation of NF-kappa B

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Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP.

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Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats

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Physical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-Y

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Interaction of human T-cell lymphotropic virus type I Tax, Ets1, and Sp1 in transactivation of the PTHrP P2 promoter

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Human TAF(II)28 interacts with the human T cell leukemia virus type I Tax transactivator and promotes its transcriptional activity

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Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA

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Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene

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Defective activation and survival of T cells lacking the Ets-1 transcription factor

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Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors

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Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

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Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity

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C-terminal phosphorylation of the serum-response factor

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Reciprocal expression of human ETS1 and ETS2 genes during T-cell activation: regulatory role for the protooncogene ETS1

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The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

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Serum, AP-1 and Ets-1 stimulate the human ets-1 promoter

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Cooperative interaction between Ets and AP-1 transcription factors regulates induction of glutathione S-transferase Ya gene expression

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Synergistic transcriptional activation of the tissue inhibitor of metalloproteinases-1 promoter via functional interaction of AP-1 and Ets-1 transcription factors

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Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factors

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Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.

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HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization

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A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions

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Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

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Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2

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CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV.

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Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells

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Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

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Identifiers

10.1074/JBC.274.18.12910

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