(Q28142883)

English

GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex

scientific article (publication date: 21 July 2000)

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scholarly article

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GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex (English)

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Wiskott-Aldrich syndrome

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Philippe Sansonetti

9

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Christophe Le Clainche

5

object named as

C Le Clainche

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author name string

M F Carlier

1

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P Nioche

2

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I Broutin-L'Hermite

3

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R Boujemaa

4

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C Egile

6

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C Garbay

7

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A Ducruix

8

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D Pantaloni

10

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language of work or name

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publication date

21 July 2000

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Journal of Biological Chemistry

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275

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21946-52

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29

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Signaling to actin dynamics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Signalling to actin: the Cdc42-N-WASP-Arp2/3 connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Activation of the yeast Arp2/3 complex by Bee1p, a WASP-family protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Actin polymerization: Where the WASP stings

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The WASp homologue Las17p functions with the WIP homologue End5p/verprolin and is essential for endocytosis in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The human WASP-interacting protein, WIP, activates the cell polarity pathway in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Waltzing with WASP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Studies of the expression of the Wiskott-Aldrich syndrome protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Crystal structure of the mammalian Grb2 adaptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The Grb2 adaptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Requirement for the adapter protein GRB2 in EGF receptor endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Effect of potent and selective inhibitors of the Grb2 SH2 domain on cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

How profilin promotes actin filament assembly in the presence of thymosin beta 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000687200

21 January 2018

Identifiers

10.1074/JBC.M000687200

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