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Tyrosine kinase SYK: essential functions for immunoreceptor signalling
scientific article (publication date: March 2000)
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Tyrosine kinase SYK: essential functions for immunoreceptor signalling
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author
Martin Turner
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
Francesco Colucci
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
James P Di Santo
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
Victor Tybulewicz
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
E Schweighoffer
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
language of work or name
English
0 references
publication date
1 March 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
number of pages
7
1 reference
based on heuristic
inferred from page(s)
published in
Trends in Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
21
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
148-154
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
cites work
Association of p72syk with the src homology-2 (SH2) domains of PLC gamma 1 in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell activation induced by novel gain-of-function mutants of Syk and ZAP-70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Syk family of protein tyrosine kinases in T-cell activation and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell activation by clustered tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for ZAP-70 in both positive and negative selection of thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: analysis of FcR gamma-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction during natural killer cell activation: inside the mind of a killer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FcR gamma chain deletion results in pleiotrophic effector cell defects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk tyrosine kinase required for mouse viability and B-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B-cell receptor regulation of peripheral B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Fc(epsilon)RIbeta subunit functions as an amplifier of Fc(epsilon)RIgamma-mediated cell activation signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the high-affinity immunoglobulin E receptor Fc epsilon RI in RBL-2H3 cells is inhibited by Syk SH2 domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initial events in Fc epsilon RI signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction by lymphocyte antigen receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clustered syk tyrosine kinase domains trigger phagocytosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Collagen receptor signalling in platelets: extending the role of the ITAM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-5699%2899%2901574-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-5699(99)01574-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PubMed publication ID
10689303
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10689303
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689303%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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