(Q28179104)

10

0 references

Jean-Charles Fruchart

9

0 references

Christophe Blanquart

object named as

Christophe Blanquart

5

0 references

Thierry Claudel

4

object named as

Thierry Claudel

0 references

Daniel Duran-Sandoval

6

object named as

Daniel Duran-Sandoval

0 references

author name string

Olivier Barbier

1

0 references

Ines Pineda Torra

2

0 references

Audrey Sirvent

3

0 references

Folkert Kuipers

7

0 references

Vladimir Kosykh

Nuclear receptors. I. Nuclear receptors and bile acid homeostasis

8

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language of work or name

English

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publication date

June 2003

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published in

Gastroenterology

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volume

124

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page(s)

1926-40

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issue

7

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cites work

1 reference

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The continuing importance of bile acids in liver and intestinal disease

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Bile acids: natural ligands for an orphan nuclear receptor

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Identification of a chemical tool for the orphan nuclear receptor FXR.

7 January 2021

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6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

7 January 2021

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Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

7 January 2021

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Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

7 January 2021

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

7 January 2021

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Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

7 January 2021

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Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

7 January 2021

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The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

7 January 2021

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Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

7 January 2021

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Characterization of rat liver bile acid acyl glucuronosyltransferase

7 January 2021

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Serum concentrations of bile acid glucuronides in hepatobiliary diseases

7 January 2021

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Analysis of bile acid glucuronides in urine. Identification of 3 alpha, 6 alpha, 12 alpha-trihydroxy-5 beta-cholanoic acid

7 January 2021

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UDP-Glucuronosyltransferases

7 January 2021

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The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

7 January 2021

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Genomic organization of the UGT2b gene cluster on human chromosome 4q13.

7 January 2021

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Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase

7 January 2021

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Structure of the human UGT2B4 gene encoding a bile acid UDP-glucuronosyltransferase

7 January 2021

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ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)

7 January 2021

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Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter

7 January 2021

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Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

7 January 2021

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Bilirubin and bile acids may modulate their own metabolism via regulating uridine diphosphate-glucuronosyltransferase expression in the rat

7 January 2021

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The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

7 January 2021

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Immortalized human hepatocytes as a tool for the study of hepatocytic (de-)differentiation

7 January 2021

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Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates

7 January 2021

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Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids

7 January 2021

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Isolation and characterization of a human orphan UDP-glucuronosyltransferase, UGT2B11.

7 January 2021

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Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene

7 January 2021

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UDP glucuronosyltransferase mRNA levels in human liver disease

7 January 2021

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Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes

7 January 2021

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

7 January 2021

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Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a

7 January 2021

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Chemical genomics: functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism

7 January 2021

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

7 January 2021

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Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding

7 January 2021

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Opposite in vitro and in vivo regulation of hepatic apolipoprotein A-I gene expression by retinoic acid. Absence of effects on apolipoprotein A-II gene expression

7 January 2021

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The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates

7 January 2021

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A retinoic acid-responsive element in the apolipoprotein AI gene distinguishes between two different retinoic acid response pathways

7 January 2021

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Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives

7 January 2021

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Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7

7 January 2021

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Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine

7 January 2021

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UDP-glucuronosyltransferases in human intestinal mucosa

7 January 2021

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Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat.

7 January 2021

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Hepatic transport of bile salts

7 January 2021

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Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3

7 January 2021

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Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

7 January 2021

1 reference

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Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

7 January 2021

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Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice

7 January 2021

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The pathophysiology of cholestasis with special reference to primary biliary cirrhosis

7 January 2021

1 reference

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Tissue distribution and induction of human multidrug resistant protein 3

7 January 2021

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Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans

7 January 2021

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Bile Salt Glucuronides: Identification and Quantitative Analysis in the Urine of Patients with Cholestasis

7 January 2021

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Odorant signal termination by olfactory UDP glucuronosyl transferase

7 January 2021

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Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation.

7 January 2021

1 reference

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