(Q28185858)

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A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

scientific article (publication date: April 2003)

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scholarly article

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A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2 (English)

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Lena Claesson-Welsh

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object named as

Lena Claesson-Welsh

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author name string

Jian Hua Qi

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Quteba Ebrahem

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Nina Moore

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Gillian Murphy

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Mark Bond

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Andrew Baker

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Bela Anand-Apte

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language of work or name

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publication date

April 2003

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Nature Medicine

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9

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4

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407-15

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis.

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Matrix-degrading proteases and angiogenesis during development and tumor formation.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22

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https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Quantitation of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus. Metalloproteinase inhibition is associated with proapoptotic activity

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Localization of the functional domains of human tissue inhibitor of metalloproteinases-3 and the effects of a Sorsby's fundus dystrophy mutation.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

based on heuristic

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Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Matrix metalloproteinase and tissue inhibitor of metalloproteinase regulation of the invasive potential of a metastatic renal cell line

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

based on heuristic

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Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

based on heuristic

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The tissue inhibitor of metalloproteinases-3 gene in breast carcinoma: identification of multiple polyadenylation sites and a stromal pattern of expression

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

based on heuristic

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Tissue inhibitor of metalloproteinase-3 is a basement membrane-associated protein that is significantly decreased in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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Tissue inhibitors of matrix metalloendopeptidases

1 reference

https://api.crossref.org/works/10.1038%2FNM846

7 January 2021

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