(Q28194880)

English

P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation

scientific article (publication date: March 2006)

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scholarly article

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P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation (English)

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author name string

H Shankar

1

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A Garcia

2

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J Prabhakar

3

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S Kim

4

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S P Kunapuli

5

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language of work or name

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publication date

March 2006

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Journal of Thrombosis and Haemostasis

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4

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3

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638-47

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PAR-4 agonist AYPGKF stimulates thromboxane production by human platelets

1 reference

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Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells

1 reference

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cPLA2 is phosphorylated and activated by MAP kinase

1 reference

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Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets

1 reference

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Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

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Identification and characterization of the cell type-specific and developmentally regulated alpha7 integrin gene promoter

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Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways

1 reference

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21 April 2017

Thromboxane A2: its generation and role in platelet activation

1 reference

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21 January 2018

A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.

1 reference

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21 January 2018

P2X(1)-mediated activation of extracellular signal-regulated kinase 2 contributes to platelet secretion and aggregation induced by collagen

1 reference

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21 January 2018

Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.

1 reference

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Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets

1 reference

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Role of p38 mitogen-activated protein kinase in thrombus formation

1 reference

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Inhibition of mitogen-activated protein kinase kinase does not impair primary activation of human platelets

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Inhibition of the MEK/ERK pathway has no effect on agonist-induced aggregation of human platelets

1 reference

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The activation by Ca2+ of platelet phospholipase A2. Effects of dibutyryl cyclic adenosine monophosphate and 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate

1 reference

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Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets

1 reference

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Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling

1 reference

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21 January 2018

Comparative safety and tolerability of clopidogrel and aspirin: results from CAPRIE. CAPRIE Steering Committee and Investigators. Clopidogrel versus aspirin in patients at risk of ischaemic events

1 reference

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Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets

1 reference

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21 January 2018

Thrombin produces phosphorylation of cytosolic phospholipase A2 by a mitogen-activated protein kinase kinase-independent mechanism in the human astrocytoma cell line 1321N1.

1 reference

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21 January 2018

The role of the Ca2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes

1 reference

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21 January 2018

Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf

1 reference

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21 January 2018

Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin

1 reference

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Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner

1 reference

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21 January 2018

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10.1111/J.1538-7836.2006.01789.X

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