(Q44403188)

2 December 2017

Inhibition of the MEK/ERK pathway has no effect on agonist-induced aggregation of human platelets (English)

1 reference

1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene

2 December 2017

1 reference

ChEBI release 2020-05-28

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00069-8

24 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00069-8

24 December 2023

author name string

Archibald McNicol

series ordinal

1

1 reference

2 December 2017

Elke C. G. Jackson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12694865

24 December 2023

language of work or name

English

0 references

publication date

1 April 2003

1 reference

2 December 2017

15 April 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12694865

full work available at URL

24 December 2023

https://api.elsevier.com/content/article/PII:S0006295203000698?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00069-8

https://api.elsevier.com/content/article/PII:S0006295203000698?httpAccept=text/plain

24 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00069-8

24 December 2023

published in

Biochemical Pharmacology

1 reference

2 December 2017

65

1 reference

2 December 2017

8

1 reference

2 December 2017

1243-1250

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

2 December 2017

1 reference

Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Incorporation of map kinases into the platelet cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Thrombin induces activation of p38 MAP kinase in human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Phosphorylation and activation of cytosolic phospholipase A2 by 38-kDa mitogen-activated protein kinase in collagen-stimulated human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Maximal epidermal growth-factor-induced cytosolic phospholipase A2 activation in vivo requires phosphorylation followed by an increased intracellular calcium concentration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Shear stress activates cytosolic phospholipase A2 (cPLA2) and MAP kinase in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a p42 mitogen-activated protein kinase-dependent phosphorylation pathway in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Cytoplasmic phospholipase A2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Negative regulation of mitogen-activated protein kinase activation by integrin alphaIIbbeta3 in platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Pharmacological inhibitors of MAPK pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Unraveling the complexities of the Raf/MAP kinase pathway for pharmacological intervention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Effects of the Mitogen-Activated Protein (MAP) Kinase Kinase Inhibitor 2-(2′-Amino-3′-methoxyphenyl)-oxanaphthalen-4-one (PD98059) on Human Platelet Activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Direct Inhibition of Cyclooxygenase-1 and -2 by the Kinase Inhibitors SB 203580 and PD 98059

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

ADP evokes biphasic Ca2+ influx in fura-2-loaded human platelets. Evidence for Ca2+ entry regulated by the intracellular Ca2+ store

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Anisomycin does not activate p38MAPK in human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

The role of protein kinase C in cell surface signal transduction and tumour promotion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Studies and perspectives of protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Resveratrol decreases early signaling events in washed platelets but has little effect on platelet in whole blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Molecular mechanisms of platelet activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Insufficient mobilization of calcium by early breakdown of phosphatidylinositol 4,5-bisphosphate for aggregation of human platelets by collagen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Dissociation of Ca2+ mobilization from breakdown of phosphatidylinositol 4,5-bisphosphate in activated human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

The mechanism of arachidonic acid release in collagen-activated human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Collagen-induced platelet activation mainly involves the protein kinase C pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

Signal transduction through MAP kinase cascades

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900069-8

inferred from DOI database lookup

7 January 2021

based on heuristic

The phospholipase C inhibitor U73122 inhibits phorbol ester-induced platelet activation

series ordinal

32

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00069-8

24 December 2023

Identifiers

1 reference

2 December 2017

1 reference