(Q28202543)

2

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Ying Luo

3

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Betty Chuang

4

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Lorien M Paulson

5

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Binh Nguyen

6

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Quinn L Deveraux

7

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Richard J Ulevitch

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

23 August 2002

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published in

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volume

277

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page(s)

30454-62

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issue

34

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cites work

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IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

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Escaping cell death: survival proteins in cancer

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Mechanisms of apoptosis avoidance in cancer.

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Dysregulation of apoptosis in cancer

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Control of programmed cell death by the baculovirus genes p35 and iap.

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An exegesis of IAPs: salvation and surprises from BIR motifs

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

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Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

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Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

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Livin, a novel inhibitor of apoptosis protein family member

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IAP family proteins--suppressors of apoptosis

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

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Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

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X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors

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X-linked IAP is a direct inhibitor of cell-death proteases

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Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2.

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TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B

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The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

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Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

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JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

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Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes

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Apoptosis signaling by death receptors.

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

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c-Jun and the transcriptional control of neuronal apoptosis

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TRAF6 is a signal transducer for interleukin-1

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

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