(Q28204452)

English

The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways

scientific article (publication date: September 2003)

In more languages

Statements

scholarly article

0 references

The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways (English)

0 references

The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways (English)

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

0 references

1 reference

based on heuristic

inferred from title

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

molecular medicine

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Adrian Newman-Tancredi

5

object named as

A. Newman-Tancredi

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

author name string

J-M Rivet

7

0 references

M. J. Millan

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

A. Gobert

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

F. Lejeune

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

A. Dekeyne

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

V. Pasteau

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

D. Cussac

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

language of work or name

0 references

publication date

September 2003

0 references

15 May 2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12750432

3 January 2024

full work available at URL

https://syndication.highwire.org/content/doi/10.1124/jpet.103.051797

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Journal of Pharmacology and Experimental Therapeutics

0 references

306

0 references

3

0 references

954-64

0 references

Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons

2

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Agonist-induced GTPgamma35S binding mediated by human 5-HT(2C) receptors expressed in human embryonic kidney 293 cells

3

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Catecholamine regulation of the prefrontal cortex

4

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

British Journal of Pharmacology

5

14

48

publication date

1956

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

6

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

The pineal gland and melatonin: molecular and pharmacologic regulation

7

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Abstracts from the XXIII CINP Congress, Montréal, June 23–27, 2002

8

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Evidence for accelerated desensitisation of 5-HT(2C) receptors following combined treatment with fluoxetine and the 5-HT(1A) receptor antagonist, WAY 100,635, in the rat

10

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Differential activation of Gq/11 and Gi(3) proteins at 5-hydroxytryptamine(2C) receptors revealed by antibody capture assays: influence of receptor reserve and relationship to agonist-directed trafficking

11

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [3H]phosphatidylinositols

12

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

The nigrostriatal dopamine system: a neglected target for 5-HT2C receptors

13

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study

15

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Role of 5-HT(2C) receptors in the control of central dopamine function

16

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Melatonin modulates the sensitivity of 5-hydroxytryptamine-2 receptor-mediated sleep-wakefulness regulation in the rat.

17

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Dopamine and melatonin in the nucleus accumbens may be implicated in the mode of action of antidepressant drugs

18

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system

19

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Serotonin and antidepressant drugs antagonize melatonin-induced behavioural changes after injection into the nucleus accumbens of rats.

21

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Mirtazapine substitution in SSRI-induced sexual dysfunction.

22

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Functional characteristics of heterologously expressed 5-HT receptors

23

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat

24

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Identification of serotonin 5HT2receptors in bovine pineal gland

25

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction

26

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Brain 5-HT1C receptors and antidepressants.

27

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms.

28

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated

29

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock.

31

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study

32

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Serotonin 2C receptor knockout mice: Autoradiographic analysis of multiple serotonin receptors

33

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram

34

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: relevance to the actions of antidepressant agents

35

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

5-HT2C receptors mediate penile erections in rats: actions of novel and selective agonists and antagonists

36

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

A novel role for serotonin in heart

37

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Inhibition of the constitutive activity of human 5-HT1A receptors by the inverse agonist, spiperone but not the neutral antagonist, WAY 100,635

38

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Effects of melatonin receptor ligands on swim test immobility

39

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Effect of agomelatine in the chronic mild stress model of depression in the rat.

40

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Entrainment of rat circadian rhythms by the melatonin agonist S-20098 requires intact suprachiasmatic nuclei but not the pineal.

41

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Melatonin receptors: molecular biology of a new family of G protein-coupled receptors

42

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Effects of SSRIs on sexual function: a critical review

43

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Circadian rhythms in depression and recovery: evidence for blunted amplitude as the main chronobiological abnormality.

46

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Depression and endogenous melatonin in postmenopausal women

48

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

American Journal of Physiology

49

280

1582

publication date

2001

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

A single oral dose of S 22153, a melatonin antagonist, blocks the phase advancing effects of melatonin in C3H mice.

50

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Regulation of extracellular dopamine by the norepinephrine transporter.

51

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Chronic exposure to melatonin receptor agonists does not alter their effects on suprachiasmatic nucleus neurons.

52

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Novel naphthalenic ligands with high affinity for the melatonin receptor

53

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting

54

1 reference

10.1124/JPET.103.051797

https://api.crossref.org/works/10.1124/JPET.103.051797

3 January 2024

Identifiers

10.1124/JPET.103.051797

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28204452&oldid=2043886286"