(Q28204878)

Molecular Genetics and Metabolism

PubMed

published in

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volume

77

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issue

1-2

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page(s)

35-43

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cites work

Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Linkage of type 2 diabetes to the glucokinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Analysis of the rat hepatocyte nuclear factor (HNF) 1 gene promoter: synergistic activation by HNF4 and HNF1 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Naturally occurring mutations in the human HNF4alpha gene impair the function of the transcription factor to a varying degree

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Liver-enriched transcription factors and hepatocyte differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mutations in the hepatocyte nuclear factor-1beta gene are associated with familial hypoplastic glomerulocystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1beta

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Two members of an HNF1 homeoprotein family are expressed in human liver

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Contribution of Known and Unknown Susceptibility Genes to Early-Onset Diabetes in Scandinavia: Evidence for Heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Exclusion of the hepatocyte nuclear factor 4alpha as a candidate gene for late-onset NIDDM linked with chromosome 20q.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: evidence for pharmacogenetics in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A transcriptional hierarchy involved in mammalian cell-type specification

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A transcription factor regulatory circuit in differentiated pancreatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

1 reference

7 January 2021

HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4alpha in Caucasians with maturity onset NIDDM

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2.

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Genome-wide search for type 2 diabetes in Japanese affected sib-pairs confirms susceptibility genes on 3q, 15q, and 20q and identifies two new candidate Loci on 7p and 11p

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Genomewide search for type 2 diabetes susceptibility genes in four American populations

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021

Rare variants identified in the HNF-4α β-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1096-7192%2802%2900150-6

7 January 2021