(Q28205958)

English

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate

scientific article (publication date: 6 December 2002)

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] CELE_Y37H9A.6

1 reference

GOA release 2020-03-11

Stephen T Safrany

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

author name string

David I Fisher

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Peter Strike

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Alexander G McLennan

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Jared L Cartwright

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

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publication date

4 October 2002

1 reference

Europe PubMed Central

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13 December 2019

number of pages

5

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

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13 December 2019

277

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13 December 2019

49

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13 December 2019

47313-47317

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Cloning, characterisation and crystallisation of a diadenosine 5',5"'-P(1),P(4)-tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Specific and nonspecific enzymes involved in the catabolism of mononucleoside and dinucleoside polyphosphates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Schizosaccharomyces pombe Aps1, a diadenosine 5',5' "-P1, P6-hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: cloning of the gene and characterization of the purified enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The g5R (D250) gene of African swine fever virus encodes a Nudix hydrolase that preferentially degrades diphosphoinositol polyphosphates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Tryptophan biosynthetic genes in eukaryotic microorganisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Mutation in the phosphoribosylpyrophosphate synthetase gene (prs) that results in simultaneous requirements for purine and pyrimidine nucleosides, nicotinamide nucleotide, histidine, and tryptophan in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Regulation of energy metabolism in macrophages during hypoxia. Roles of fructose 2,6-bisphosphate and ribose 1,5-bisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The NADH diphosphatase encoded by the Saccharomyces cerevisiae NPY1 nudix hydrolase gene is located in peroxisomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Cloning, expression and characterization of YSA1H, a human adenosine 5′-diphosphosugar pyrophosphatase possessing a MutT motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Cloning, expression and characterisation of a human Nudix hydrolase specific for adenosine 5'-diphosphoribose (ADP-ribose)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

A continuous spectrophotometric assay for inorganic phosphate and for measuring phosphate release kinetics in biological systems

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg(2+)-and/or Mn(2+)-dependent hydrolases acting on ADP-ribose.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The route of non-enzymic and enzymic breakdown of 5-phosphoribosyl 1-pyrophosphate to ribose 1-phosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Inhibition of cellular growth by increased guanine nucleotide pools. Characterization of an Escherichia coli mutant with a guanosine kinase that is insensitive to feedback inhibition by GTP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

An accurate method for estimating 5-phosphoribosyl 1-pyrophosphate in animal tissues with the use of acid extraction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Concentration, synthesis and utilization of phosphoribosylpyrophosphate in lymphocytes of five mammalian species

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Physiological concentrations of purines and pyrimidines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

High-performance liquid chromatographic assay of the diadenosine polyphosphates in human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Regiospecificity of the hydrolysis of diadenosine polyphosphates catalyzed by three specific pyrophosphohydrolases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209795200

21 January 2018

Identifiers

10.1074/JBC.M209795200

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12370170%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

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