(Q28206048)

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Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

scientific article (publication date: 15 June 2001)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11262396%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11262396%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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Sophie Tartare-Deckert

1

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5 November 2019

author name string

Monthouel MN

2

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5 November 2019

Charvet C

3

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5 November 2019

Foucault I

4

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5 November 2019

Van Obberghen E

5

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5 November 2019

Bernard A

6

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5 November 2019

Altman A

7

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5 November 2019

Deckert M

8

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5 November 2019

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publication date

21 March 2001

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5 November 2019

number of pages

9

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Journal of Biological Chemistry

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5 November 2019

276

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5 November 2019

24

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5 November 2019

20849-20857

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5 November 2019

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

T cell antigen-receptor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Ternary complex factors: growth factor regulated transcriptional activators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Regulatory and signaling properties of the Vav family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

A functional T-cell receptor signaling pathway is required for p95vav activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav family proteins couple to diverse cell surface receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav2 is an activator of Cdc42, Rac1, and RhoA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The role of SLP-76 and LAT in lymphocyte development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Adapter proteins in lymphocyte antigen-receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Lymphocyte signaling: Cbl sets the threshold for autoimmunity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Cbl: complex formation and functional implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Cbl-b regulates the CD28 dependence of T-cell activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The Actin Cytoskeleton and Lymphocyte Activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Involvement of p21ras activation in T cell CD69 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Raf-1 provides a dominant but not exclusive signal for the induction of CD69 expression on T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010588200

21 January 2018

Identifiers

10.1074/JBC.M010588200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11262396%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11262396%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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