(Q28208312)

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

31 March 2020

1 reference

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

31 March 2020

1 reference

Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma

31 March 2020

1 reference

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

31 March 2020

1 reference

Peutz-Jeghers syndrome: experience with twenty patients in five generations

31 March 2020

1 reference

Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4.

31 March 2020

1 reference

Very high risk of cancer in familial Peutz-Jeghers syndrome

31 March 2020

1 reference

Increased risk for cancer in patients with the Peutz-Jeghers syndrome

31 March 2020

1 reference

Increased risk of cancer in the Peutz-Jeghers syndrome

31 March 2020

1 reference

Cancer and the Peutz-Jeghers syndrome

31 March 2020

1 reference

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome

31 March 2020

1 reference

STK11/LKB1 germline mutations are not identified in most Peutz-Jeghers syndrome patients

31 March 2020

1 reference

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

31 March 2020

1 reference

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.

31 March 2020

1 reference

Hamartomatous polyposis syndromes: molecular genetics, neoplastic risk, and surveillance recommendations

31 March 2020

1 reference

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

31 March 2020

1 reference

A juvenile polyposis tumor suppressor locus at 10q22 is deleted from nonepithelial cells in the lamina propria.

31 March 2020

1 reference

ONCOGENESIS: Landscaping the Cancer Terrain

31 March 2020

1 reference

Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence.

31 March 2020

1 reference

Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos

31 March 2020

1 reference

Identification of genes required for cytoplasmic localization in early C. elegans embryos

31 March 2020

1 reference

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo

31 March 2020

1 reference

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

31 March 2020

1 reference

Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients

31 March 2020

1 reference

The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase

31 March 2020

1 reference

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

31 March 2020

1 reference

Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix

31 March 2020

1 reference

In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours

31 March 2020

1 reference

Stem cells in gastrointestinal epithelium: numbers, characteristics and death

31 March 2020

1 reference

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

31 March 2020

1 reference

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

31 March 2020

1 reference

Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development.

31 March 2020

1 reference

Peutz-Jeghers syndrome. Case report with angiographic evaluation

31 March 2020

1 reference

Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

31 March 2020

1 reference

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

31 March 2020

1 reference

Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1).

31 March 2020

1 reference

LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest

31 March 2020

1 reference

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

31 March 2020

1 reference