(Q28211693)

English

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11297520%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth (English)

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6 November 2019

Serine/threonine kinase 11

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GOA release 2020-03-11

phosphorylation

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based on heuristic

inferred from title

3

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6 November 2019

Simon J. Arthur

5

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6 November 2019

9

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6 November 2019

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G P Sapkota

1

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6 November 2019

A Kieloch

2

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6 November 2019

S Lain

4

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6 November 2019

M R Williams

6

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6 November 2019

N Morrice

7

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6 November 2019

M Deak

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6 November 2019

publication date

31 January 2001

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6 November 2019

language of work or name

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Journal of Biological Chemistry

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6 November 2019

276

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6 November 2019

22

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6 November 2019

19469-19482

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6 November 2019

The molecular basis and clinical aspects of Peutz-Jeghers syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Peutz-Jeghers syndrome: 78-year follow-up of the original family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Ribosomal S6 kinase signaling and the control of translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Protein prenylation: molecular mechanisms and functional consequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Molecular pharmacology of protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Identification of Regulatory Phosphorylation Sites in Mitogen-activated Protein Kinase (MAPK)-activated Protein Kinase-1a/p90 That Are Inducible by MAPK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid example

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The cyclic AMP-mediated stimulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Serine/threonine protein kinases and apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Identifiers

10.1074/JBC.M009953200

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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6 November 2019

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11297520%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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