(Q28208567)

English

Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases

scientific article (publication date: June 2001)

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scholarly article

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Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases (English)

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9-cis-retinoic acid metabolic process

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Gene Ontology release 2020-05-02

Gene Ontology ID

9-cis-retinoic acid biosynthetic process

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Gene Ontology release 2020-05-02

Gene Ontology ID

author name string

K Tryggvason

1

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A Romert

2

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U Eriksson

3

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language of work or name

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publication date

1 June 2001

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Journal of Biological Chemistry

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276

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19253-8

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22

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Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Activity of human 11-cis-retinol dehydrogenase (Rdh5) with steroids and retinoids and expression of its mRNA in extra-ocular human tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Cloning of a rat cDNA encoding retinol dehydrogenase isozyme type III.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

cDNA cloning, tissue distribution, and substrate characteristics of a cis-Retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

cDNA cloning and characterization of a new human microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3alpha-hydroxysteroids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Gene structure, expression analysis, and membrane topology of RDH4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Primary structure of human 11-cis retinol dehydrogenase and organization and chromosomal localization of the corresponding gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Retinoids selective for retinoid X receptor response pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Production of single-stranded plasmid DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Oxidized redox state of glutathione in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

The levels of nicotinamide nucleotides in liver microsomes and their possible significance to the function of hexose phosphate dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Cloning of a cDNA for liver microsomal retinol dehydrogenase. A tissue-specific, short-chain alcohol dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Cloning of a cDNA for a second retinol dehydrogenase type II. Expression of its mRNA relative to type I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

Impaired retinol utilization in Adh4 alcohol dehydrogenase mutant mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100215200

21 January 2018

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10.1074/JBC.M100215200

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