(Q28210468)

English

Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells

scientific article (publication date: 20 February 2003)

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Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells (English)

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Brian P Schlegel

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Lea M Starita

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Jeffrey D Parvin

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publication date

20 February 2003

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22

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7

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983-91

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BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 required for transcription-coupled repair of oxidative DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 is associated with the centrosome during mitosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromatin remodeling and activation of chromosomal DNA replication by an acidic transcriptional activation domain from BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Centrosome amplification drives chromosomal instability in breast tumor development

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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RNA helicase A mediates association of CBP with RNA polymerase II

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 is a component of the RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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A cellular defense pathway regulating transcription through poly(ADP-ribosyl)ation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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PARP is important for genomic stability but dispensable in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206195

7 January 2021

based on heuristic

inferred from DOI database lookup

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