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Mouse models for human DNA mismatch-repair gene defects
scientific article (publication date: July 2002)
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scholarly article
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review article
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Europe PubMed Central
title
Mouse models for human DNA mismatch-repair gene defects
(English)
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main subject
DNA mismatch repair
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based on heuristic
inferred from title
author name string
Kaichun Wei
series ordinal
1
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Raju Kucherlapati
series ordinal
2
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Winfried Edelmann
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3
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language of work or name
English
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publication date
July 2002
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published in
Trends in Molecular Medicine
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volume
8
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issue
7
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page(s)
346-53
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cites work
DNA mismatch repair and cancer
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Crossref
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The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)
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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
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Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer
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MutS homologs in mammalian cells
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7 January 2021
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Biochemistry and genetics of eukaryotic mismatch repair
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reference URL
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7 January 2021
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Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair
1 reference
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7 January 2021
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Replication errors: cha(lle)nging the genome
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Conserved properties between functionally distinct MutS homologs in yeast
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Mammalian MutS homologue 5 is required for chromosome pairing in meiosis
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7 January 2021
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Mammalian DNA mismatch repair
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
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7 January 2021
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Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
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MSH2 deficient mice are viable and susceptible to lymphoid tumours
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Crossref
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7 January 2021
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Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity
1 reference
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The Muir-Torre syndrome: A 25-year retrospect
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Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria
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Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts
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7 January 2021
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inferred from DOI database lookup
HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions
1 reference
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Crossref
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7 January 2021
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Mutations of GTBP in genetically unstable cells
1 reference
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Crossref
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7 January 2021
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Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility
1 reference
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Crossref
reference URL
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7 January 2021
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Familial endometrial cancer in female carriers of MSH6 germline mutations
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7 January 2021
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Cloning and expression analysis of a meiosis-specific MutS homolog: the human MSH4 gene
1 reference
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Crossref
reference URL
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7 January 2021
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Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene
1 reference
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Crossref
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7 January 2021
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Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis
1 reference
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Crossref
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7 January 2021
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Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over
1 reference
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7 January 2021
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Meiotic pachytene arrest in MLH1-deficient mice
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7 January 2021
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Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
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7 January 2021
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inferred from DOI database lookup
Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair
1 reference
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Crossref
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7 January 2021
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Alternative splicing of hMSH4: two isoforms in testis and abnormal transcripts in somatic tissues
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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inferred from DOI database lookup
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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Different mutator phenotypes in Mlh1- versus Pms2-deficient mice
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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inferred from DOI database lookup
Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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inferred from DOI database lookup
Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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inferred from DOI database lookup
Strand-specific mismatch repair in mammalian cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the mismatch repair system in temozolomide-induced apoptosis
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mismatch repair provokes chromosome aberrations in hamster cells treated with methylating agents or 6-thioguanine, but not with ethylating agents
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA mismatch repair and genetic instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The interaction of DNA mismatch repair proteins with human exonuclease I
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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inferred from DOI database lookup
Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902359-6
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7 January 2021
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Identifiers
DOI
10.1016/S1471-4914(02)02359-6
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4511869
OpenCitations bibliographic resource ID
4511869
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4511869
PubMed publication ID
12114115
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4511869
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