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Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity
scientific journal article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
title
Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity
(English)
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
main subject
MutS homolog 2
1 reference
stated in
GOA release 2020-03-11
Eukaryotic elongation factor, selenocysteine-tRNA-specific
1 reference
stated in
GOA release 2020-03-11
author name string
R. Smits
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
N. Hofland
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
W. Edelmann
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
M. Geugien
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
S. Jagmohan-Changur
series ordinal
5
1 reference
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PubMed
PubMed ID
10992298
retrieved
24 January 2017
C. Albuquerque
series ordinal
6
1 reference
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PubMed
PubMed ID
10992298
retrieved
24 January 2017
C. Breukel
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
R. Kucherlapati
series ordinal
8
1 reference
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PubMed
PubMed ID
10992298
retrieved
24 January 2017
M. F. Kielman
series ordinal
9
1 reference
stated in
PubMed
PubMed ID
10992298
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24 January 2017
R. Fodde
series ordinal
10
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
publication date
1 November 2000
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
published in
Genes, Chromosomes and Cancer
1 reference
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PubMed
PubMed ID
10992298
retrieved
24 January 2017
volume
29
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
page(s)
229–239
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
10992298
retrieved
24 January 2017
cites work
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Chain-terminating mutations in the APC gene lead to alterations in APC RNA and protein concentration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Identification and characterization of the familial adenomatous polyposis coli gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Genetic instabilities in human cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
APC mutations occur early during colorectal tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
MSH2 deficient mice are viable and susceptible to lymphoid tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Association of the APC gene product with beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
The APC gene product in normal and tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Association of the APC tumor suppressor protein with catenins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Germline mutations in the 3' part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Beta-catenin: a key mediator of Wnt signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Selection, the mutation rate and cancer: Ensuring that the tail does not wag the dog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F1098-2264%282000%299999%3A9999%3C%3A%3AAID-GCC1033%3E3.0.CO%3B2-R
retrieved
21 January 2018
Identifiers
DOI
10.1002/1098-2264(2000)9999:9999<::AID-GCC1033>3.0.CO;2-R
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667171
OpenCitations bibliographic resource ID
667171
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667171
PubMed ID
10992298
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
667171
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