(Q28214436)

English

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators

scientific article (publication date: 13 September 2002)

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Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators (English)

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author name string

Gyesik Min

1

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Hwajin Kim

2

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Yangjin Bae

3

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Larry Petz

4

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Jongsook Kim Kemper

5

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language of work or name

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publication date

13 September 2002

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Journal of Biological Chemistry

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277

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37

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34626-33

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The steroid and thyroid hormone receptor superfamily

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Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

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Different positioning of the ligand-binding domain helix 12 and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists

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10.1074/JBC.M205239200

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