Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28214997)
Watch
English
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
scientific article (publication date: 25 June 2002)
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
title
Sonic hedgehog induces the segregation of patched and smoothened in endosomes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author
Henk Roelink
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
John P Incardona
series ordinal
1
object named as
John P Incardona
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
author name string
Jean Gruenberg
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
language of work or name
English
0 references
publication date
1 June 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
published in
Current Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
volume
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
page(s)
983-995
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
cites work
The specification of neuronal identity by graded Sonic Hedgehog signalling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signaling in animal development: paradigms and principles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical evidence that patched is the Hedgehog receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog and patched in neural development and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of two patched receptors for the vertebrate hedgehog protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog signaling by the patched-smoothened receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signal transduction: from flies to vertebrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual roles for patched in sequestering and transducing Hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular cholesterol trafficking: role of the NPC1 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol in signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating Smoothened mutations in sporadic basal-cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retrieval of TGN proteins from the cell surface requires endosomal acidification.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vacuolar ATPase inactivation blocks recycling to the trans-Golgi network from the plasma membrane.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Animal cell lysosomes rapidly exchange membrane proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G protein-coupled receptor adaptation mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Teratogen-mediated inhibition of target tissue response to Shh signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulated endocytic routing modulates wingless signaling in Drosophila embryos.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jamming the endosomal system: lipid rafts and lysosomal storage diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transmembrane molecular pump activity of Niemann-Pick C1 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multicolour imaging of post-Golgi sorting and trafficking in live cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How proteins move lipids and lipids move proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of lipid rafts in membrane transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900895-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0960-9822(02)00895-3
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3138007
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
OpenCitations bibliographic resource ID
3138007
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3138007
PubMed publication ID
12123571
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3138007
stated in
Europe PubMed Central
PubMed publication ID
12123571
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12123571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
11 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit