(Q28215982)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

1 reference

title

Genetics of type 1 diabetes mellitus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

main subject

type-1 diabetes

0 references

language of work or name

English

0 references

publication date

1 August 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

235-249

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Positional cloning of the APECED gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin-dependent) diabetes mellitus. World Health Organization DIAMOND Project Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Histocompatibility (HL-A) Antigens, Lymphocytotoxic Antibodies and Tissue Antibodies in Patients with Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

HL-A antigens and diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A genome-wide search for human type 1 diabetes susceptibility genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Susceptibility to insulin-dependent diabetes mellitus maps to a locus (IDDM11) on human chromosome 14q24.3-q31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

On the pathogenesis of IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The future of genetic studies of complex human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Characterization of single-nucleotide polymorphisms in coding regions of human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

High-resolution haplotype structure in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genomewide scans of complex human diseases: true linkage is hard to find

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

21 January 2018

Map of the human MHC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Unlinking tumor necrosis factor biology from the major histocompatibility complex: lessons from human genetics and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Susceptibility to type I diabetes: HLA-DQ and DR revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Invited anniversary review: HLA associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

HLA-DQ locus of the human leukocyte antigen complex and type 1 diabetes mellitus: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Correlations between the incidence of childhood-onset type I diabetes in Europe and HLA genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A unified hypothesis for the complex genetics of HLA associations with IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The role of MHC class II molecules in susceptibility to type I diabetes: identification of peptide epitopes and characterization of the T cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

HLA-DQB1 codon 57 is critical for peptide binding and recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

High frequency of aspartic acid at position 57 of HLA-DQ beta-chain in Japanese IDDM patients and nondiabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Association of HLA-DPB1*0301 with IDDM in Mexican-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Family study of linkage disequilibrium between TAP2 transporter and HLA class II genes. Absence of TAP2 contribution to association with insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

No independent associations of LMP2 and LMP7 polymorphisms with susceptibility to develop IDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The susceptibility to insulin-dependent diabetes mellitus is associated with C4 allotypes independently of the association with HLA-DQ alleles in HLA-DR3,4 heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A tumour necrosis factor beta gene polymorphism in relation to monokine secretion and insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Homozygous parent affected sib pair method for detecting disease predisposing variants: application to insulin dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-a and TNF-0 by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Cytokine gene polymorphism in human disease: on-line databases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Cytokine gene polymorphism in human disease: on-line databases, supplement 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Polymorphism at the 5' end flanking region of the insulin gene is associated with reduced insulin secretion in healthy individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The human insulin gene linked polymorphic region exhibits an altered DNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Aberrant expression of tissue-specific proteins in the thymus: a hypothesis for the development of central tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Linkage of type I diabetes to 15q26 (IDDM3) in the Danish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Fine mapping of the diabetes-susceptibility locus, IDDM4, on chromosome 11q13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A transcript map encompassing the multiple endocrine neoplasia type-1 (MEN1) locus on chromosome 11q13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

beta-cell apoptosis: stimuli and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Cloning of a novel member of the low-density lipoprotein receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Antioxidants, NFkappaB activation, and diabetogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The polymorphic 43Thr bcl-2 protein confers relative resistance to autoimmunity: an analytical evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

No evidence of a functionally significant polymorphism of the BCL2 gene in Danish, Finnish and Basque type 1 diabetes families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Characterization of polymorphisms of an interleukin 1 receptor type 1 gene (IL1RI) promotor region (P2) and their relation to insulin-dependent diabetes mellitus (IDDM). The Danish Study Group of Diabetes in Childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Characterization of new polymorphisms in the 5' UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Linkage disequilibrium testing of four interleukin-1 gene-cluster polymorphisms in Danish multiplex families with insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings. The Danish Study Group of Diabetes in Childhood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

All LODs are not created equal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Isolation, characterization, and chromosomal localization of the human ENSA gene that encodes alpha-endosulfine, a regulator of beta-cell K(ATP) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Complete cDNA sequence and genomic organization of a human pancreas-specific gene homologous to Caenorhabditis elegans sel-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

SEL1L, the human homolog of C. elegans sel-1: refined physical mapping, gene structure and identification of polymorphic markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Notch signal transduction: a real rip and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Notch signalling controls pancreatic cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Control of endodermal endocrine development by Hes-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Complete mutation scanning of the human SEL 1L gene: a candidate gene for type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

CTLA4 gene haplotypes cannot protect from IDDM in the presence of high-risk HLA DQ8 or DQ2 alleles in German families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Association of CTLA-4 polymorphism with positive anti-GAD antibody in Japanese subjects with type 1 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

IDDM12 (CTLA4) on 2q33 and IDDM13 on 2q34 in genetic susceptibility to type 1 diabetes (insulin-dependent).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

CTLA-4 gene expression is influenced by promoter and exon 1 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

CTLA-4: a negative regulator of autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

ICOS co-stimulatory receptor is essential for T-cell activation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

ICOS is essential for effective T-helper-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

ICOS is critical for CD40-mediated antibody class switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Refinement of the 6q chromosomal region implicated in transient neonatal diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Immunoglobulin allotypes (GM and KM) and their interactions with HLA antigens in autoimmune diseases: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Infectious Th1 and Th2 autoimmunity in diabetes-prone mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

IL-12: a key cytokine in immune regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

IL-12 unmasks latent autoimmune disease in resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic polymorphism of IL-12 p40 gene in immune-mediated disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Age of diagnosis-based linkage analysis in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Clinical and molecular genetic analysis of 19 Wolfram syndrome kindreds demonstrating a wide spectrum of mutations in WFS1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Use of cod liver oil during pregnancy associated with lower risk of Type I diabetes in the offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Immunomodulatory role of 1,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Vitamin D receptor gene polymorphisms influence insulin secretion in Bangladeshi Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Molecular epidemiology of vitamin D receptor gene variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Affected sibpair linkage tests for multiple linked susceptibility genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Multi-locus nonparametric linkage analysis of complex trait loci with neural networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The NOD mouse model of type 1 diabetes: as good as it gets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence for a new Graves disease susceptibility locus at chromosome 18q21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Modeling of HLA class II susceptibility to Type I diabetes reveals an effect associated with DPB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

No evidence of association of chromosome 2 q with Type I diabetes in the Basque population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Possible association between CTLA4 DNA polymorphisms and early onset type 1 diabetes in a UK population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Association studies of CTLA-4, CD28, and ICOS gene polymorphisms with type 1 diabetes in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Evidence for a locus (IDDM16) in the immunoglobulin heavy chain region on chromosome 14q32.3 producing susceptibility to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

An association between type 1 diabetes and the interleukin-1 receptor type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Monokine Antagonism Is Reduced in Patients With IDDM

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

No evidence forSEL1L as a candidate gene forIDDM11-conferred susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Haplotype tagging for the identification of common disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

Productivity losses associated with diabetes in the US

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Epistatic effects of genes encoding tumor necrosis factor-alpha, immunoglobulin allotypes, and HLA antigens on susceptibility to non-insulin-dependent (type 2) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

A search for type 1 diabetes susceptibility genes in families from the United Kingdom

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Linkage and association between insulin-dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Population genetics--making sense out of sequence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Closing in on type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

HLA associations in insulin-dependent diabetes mellitus: no independent association to particular DP genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The HLA-DPB1--associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

TNFa Microsatellite Polymorphism Modulates the Risk of IDDM in Caucasians With the High-Risk Genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Restriction Fragment Length Polymorphism of the Insulin Gene in Diabetes Mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

DNA insertion sequences near the insulin gene affect glucose regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The human insulin gene-linked polymorphic region adopts a G-quartet structure in chromatin assembled in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Class III alleles of the variable number of tandem repeat insulin polymorphism associated with silencing of thymic insulin predispose to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Fas and Fas ligand-mediated apoptosis and its role in autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Fine-mapping of the type 1 diabetes locus (IDDM4) on chromosome 11q and evaluation of two candidate genes (FADD and GALN) by affected sibpair and linkage-disequilibrium analyses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Saturation multipoint linkage mapping of chromosome 6q in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Close genetic linkage between diabetes mellitus and kidd blood group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Association of polymorphism in the NeuroD/BETA2 gene with type 1 diabetes in the Japanese

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Physical and genetic mapping of IDDM8 on chromosome 6q27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

No major role for the CTLA-4 gene in the association of autoimmune thyroid disease with IDDM

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

CTLA4 gene polymorphism correlates with the mode of onset and presence of ICA512 Ab in Japanese type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The length of the CTLA-4 microsatellite (AT)N-repeat affects the risk for type 1 diabetes. Diabetes Incidence in Sweden Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Association of CTLA4 gene A-G polymorphism with type 1 diabetes in Chinese children

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell costimulatory interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Transient neonatal diabetes: widening the understanding of the etiopathogenesis of diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Complete primary structure, chromosomal localisation, and definition of polymorphisms of the gene encoding the human interleukin-12 p40 subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Interleukin 12 and autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

The polymorphism in the 3' untranslated region of IL12B has a negligible effect on the susceptibility to develop type 1 diabetes in Norway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. The EURODIAB Substudy 2 Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Linkage analyses in type I diabetes mellitus using CASPAR, a software and statistical program for conditional analysis of polygenic diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

A genome screen for multiple sclerosis in Sardinian multiplex families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Candidate gene region 15q26 and genetic susceptibility to coeliac disease in Finnish families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Linkage of rheumatoid arthritis to insulin-dependent diabetes mellitus loci: Evidence supporting a hypothesis for the existence of common autoimmune susceptibility loci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

A genome-wide family-based linkage study of coeliac disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GENE.6363875

7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6363875

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140742%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 November 2019

1011436511

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017