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Molecular interactions of SHP1 and SHP2 in IL-3-signalling
scientific article (publication date: March 2002)
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scholarly article
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
title
Molecular interactions of SHP1 and SHP2 in IL-3-signalling
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
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6 December 2019
main subject
molecular interaction
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author
Helen Wheadon
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
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6 December 2019
Melanie Welham
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Melanie J Welham
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
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6 December 2019
Nicholas R.D. Paling
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Nicholas R D Paling
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
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6 December 2019
language of work or name
English
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publication date
1 March 2002
1 reference
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Europe PubMed Central
PubMed publication ID
11812650
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
number of pages
11
1 reference
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inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
volume
14
1 reference
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
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6 December 2019
issue
3
1 reference
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Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
page(s)
219-229
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
cites work
Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular structure of the IL‐3, GM‐CSF and IL‐5 receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
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inferred from DOI database lookup
A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The hematopoietin receptor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein tyrosine phosphatases in signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of PTP1C mutation as the genetic defect in motheaten and viable motheaten mice: a step toward defining the roles of protein tyrosine phosphatases in the regulation of hemopoietic cell differentiation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shp-2 has a positive regulatory role in ES cell differentiation and proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src homology 2 protein tyrosine phosphatase (SHPTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of dominant negative mutant SHPTP2 attenuates phosphatidylinositol 3'-kinase activity via modulation of phosphorylation of insulin receptor substrate-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin and IL-3 induce tyrosine phosphorylation of CrkL and its association with Shc, SHP-2, and Cbl in hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of proteins that inhibit signalling through tyrosine kinase receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the tyrosine phosphatase SHP-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shc associates with the IL-3 receptor β subunit, SHIP and Gab2 following IL-3 stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of two SHP-2-associated binding proteins and potential substrates in hematopoietic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural determinants of SHP-2 function and specificity in Xenopus mesoderm induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both SH2 domains are involved in interaction of SHP-1 with the epidermal growth factor receptor but cannot confer receptor-directed activity to SHP-1/SHP-2 chimera
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2 domains recognize specific phosphopeptide sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900241-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0898-6568(01)00241-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
PubMed publication ID
11812650
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11812650
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11812650%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 December 2019
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