(Q28216739)

English

Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases

scientific article (publication date: 12 April 2002)

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scholarly article

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Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases (English)

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Sirtuin 1 Dmel_CG5216

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GOA release 2020-03-11

5

object named as

Eric Verdin

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author name string

Margie T Borra

1

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Forest J O'Neill

2

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Michael D Jackson

3

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Brett Marshall

4

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Kathy R Foltz

6

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John M Denu

7

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language of work or name

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publication date

12 April 2002

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Journal of Biological Chemistry

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277

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12632-41

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15

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Histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Protein modules that manipulate histone tails for chromatin regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Signaling to chromatin through histone modifications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

25 years after the nucleosome model: chromatin modifications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

The human histone deacetylase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

An unusual form of transcriptional silencing in yeast ribosomal DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Silencing and heritable domains of gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Common themes in mechanisms of gene silencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

SIR2 and aging--the exception that proves the rule.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Enzymatic activities of Sir2 and chromatin silencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

The Sir2 protein family: A novel deacetylase for gene silencing and more

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Gene silencing: two faces of SIR2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Post-translational modification of p53 protein in response to ionizing radiation analyzed by mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Histone deacetylases: silencers for hire.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Identification of PLCgamma-dependent and -independent events during fertilization of sea urchin eggs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Structure of the histone deacetylase SIRT2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

A CENTENNIAL DEBT OF DEVELOPMENTAL BIOLOGY TO THE SEA URCHIN.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Activation of MPF at meiosis reinitiation in starfish oocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

A new model for nuclear envelope breakdown.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Fertilization blocks apoptosis of starfish eggs by inactivation of the MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Separate activation of the cytoplasmic and nuclear calcium pools in maturing starfish oocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Effects of 1-methyladenine on nuclear Ca2+ transients and meiosis resumption in starfish oocytes are mimicked by the nuclear injection of inositol 1,4,5-trisphosphate and cADP-ribose.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Ins and outs of meiosis in ascidians.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Immunocyte Ca2+ influx system mediated by LTRPC2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Crystal structure of a SIR2 homolog-NAD complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

c-Mos forces the mitotic cell cycle to undergo meiosis II to produce haploid gametes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Evidence that fertilization activates starfish eggs by sequential activation of a Src-like kinase and phospholipase cgamma.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Calcium release at fertilization in starfish eggs is mediated by phospholipase Cgamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111830200

21 January 2018

Identifiers

10.1074/JBC.M111830200

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