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Regulation of APC-Cdc20 by the spindle checkpoint
scientific article (publication date: December 2002)
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scholarly article
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review article
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Europe PubMed Central
title
Regulation of APC-Cdc20 by the spindle checkpoint
(English)
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author name string
Hongtao Yu
series ordinal
1
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language of work or name
English
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publication date
December 2002
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published in
Current Opinion in Cell Biology
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volume
14
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issue
6
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page(s)
706-14
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cites work
Splitting the chromosome: cutting the ties that bind sister chromatids
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7 January 2021
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Bi-orienting chromosomes on the mitotic spindle.
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7 January 2021
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The anaphase-promoting complex: proteolysis in mitosis and beyond
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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Chromosome segregation and cancer: cutting through the mystery
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7 January 2021
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Sex matters in meiosis
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7 January 2021
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The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling
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7 January 2021
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The mitotic spindle checkpoint
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7 January 2021
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Waiting for anaphase: Mad2 and the spindle assembly checkpoint
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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A new view of the spindle checkpoint
1 reference
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7 January 2021
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The spindle checkpoint: two transitions, two pathways
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7 January 2021
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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores
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7 January 2021
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inferred from DOI database lookup
Mitotic forces control a cell-cycle checkpoint
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7 January 2021
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How cells get the right chromosomes
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints
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7 January 2021
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Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Requirement of the spindle checkpoint for proper chromosome segregation in budding yeast meiosis
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7 January 2021
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Lack of tension at kinetochores activates the spindle checkpoint in budding yeast
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7 January 2021
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Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Mitosis: aurora gives chromosomes a healthy stretch
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kinase activity of aurora B is required for kinetochore-microtubule interactions during mitosis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
CENP-E as an essential component of the mitotic checkpoint in vitro.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Feedback control of mitosis in budding yeast
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7 January 2021
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inferred from DOI database lookup
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
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inferred from DOI database lookup
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spindle checkpoint requires Mad1-bound and Mad1-free Mad2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle: Waiters serving the Destruction machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900382-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(02)00382-4
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3356803
OpenCitations bibliographic resource ID
3356803
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3356803
PubMed publication ID
12473343
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3356803
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