(Q28217452)

English

ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation

scientific article (publication date: 22 August 2002)

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scholarly article

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ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation (English)

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phosphorylation

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based on heuristic

inferred from title

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based on heuristic

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author name string

Kevin B Morrison

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Cristina E Tognon

2

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Mathew J Garnett

3

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Cheri Deal

4

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Poul H B Sorensen

5

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language of work or name

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publication date

22 August 2002

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21

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37

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5684-95

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The IGF-I receptor in cancer research

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The contradictions of the insulin-like growth factor 1 receptor

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Trisomy 11 and other nonrandom trisomies in congenital fibrosarcoma

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Mutant IGF-I receptors as dominant negatives for growth and transformation

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Association of insulin receptor substrate 1 with simian virus 40 large T antigen

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Fibromatosis and fibrosarcoma in infancy and childhood

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PI3K: downstream AKTion blocks apoptosis

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

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DBI-1, a novel gene related to the notch family, modulates mitogenic response to insulin-like growth factor 1.

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Ras effectors and their role in mitogenesis and oncogenesis

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A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

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Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1.

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Insulin signal transduction and the IRS proteins

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Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis

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Ultrastructure of cellular congenital mesoblastic nephroma.

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Production of high-titer helper-free retroviruses by transient transfection

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Imprinting of IGF2, insulin-dependent diabetes, immune function, and apoptosis: a hypothesis

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Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant

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Tissue-specific expression of the human tropomyosin gene involved in the generation of the trk oncogene

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Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia

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Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

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Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor

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Involvement of IGF-II in human cancer.

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The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

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Insulin-like growth factor I receptor signaling in transformation by src oncogenes

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The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

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Rational basis for Trk inhibition therapy for prostate cancer.

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Dysregulation of the type 1 IGF receptor as a paradigm in tumor progression.

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Isolation of DICE1: a gene frequently affected by LOH and downregulated in lung carcinomas

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Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

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The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulin

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Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors

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7 January 2021

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Congenital mesoblastic nephroma and trisomy 11

1 reference

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

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Presence or absence of trisomy 11 is correlated with histologic subtype in congenital mesoblastic nephroma

1 reference

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Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid

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Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains

1 reference

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Fibrosarcoma in infants and children. Application of new techniques.

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1205669

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Springer Nature article ID

10.1038/sj.onc.1205669

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