(Q34103628)

31 July 2017

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title

The contradictions of the insulin-like growth factor 1 receptor (English)

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31 July 2017

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Baserga R

1

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PubMed ID

11114737

31 July 2017

language of work or name

English

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publication date

1 November 2000

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31 July 2017

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31 July 2017

19

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31 July 2017

49

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31 July 2017

5574-5581

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203854

31 July 2017

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Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo

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Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

21 January 2018

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14-3-3 (epsilon) interacts with the insulin-like growth factor I receptor and insulin receptor substrate I in a phosphoserine-dependent manner

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Insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the platelet-derived growth factor receptor

21 January 2018

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Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

21 January 2018

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14-3-3 proteins interact with the insulin-like growth factor receptor but not the insulin receptor

21 January 2018

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Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

21 January 2018

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Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis

21 January 2018

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DBI-1, a novel gene related to the notch family, modulates mitogenic response to insulin-like growth factor 1.

21 January 2018

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Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor

21 January 2018

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

21 January 2018

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Differential regulation of insulin receptor substrate-2 and mitogen-activated protein kinase tyrosine phosphorylation by phosphatidylinositol 3-kinase inhibitors in SH-SY5Y human neuroblastoma cells.

21 January 2018

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Inhibition of myeloid differentiation by the helix-loop-helix protein Id

21 January 2018

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Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)

21 January 2018

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

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Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

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Different effects on mitogenesis and transformation of a mutation at tyrosine 1251 of the insulin-like growth factor I receptor

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Drosophila S6 kinase: a regulator of cell size

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Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis

21 January 2018

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Signaling networks--do all roads lead to the same genes?

21 January 2018

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Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

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Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

21 January 2018

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Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant

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The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.

21 January 2018

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Insulin and IGF-I receptors signaling in protection from apoptosis

21 January 2018

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IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation

21 January 2018

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Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

21 January 2018

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Suppression of insulin-like growth factor type I receptor by a triple-helix strategy inhibits IGF-I transcription and tumorigenic potential of rat C6 glioblastoma cells

21 January 2018

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Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling.

21 January 2018

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

21 January 2018

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

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Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma

21 January 2018

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

21 January 2018

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Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Overexpression of insulin-like growth factor-II induces accelerated myoblast differentiation

21 January 2018

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Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor

21 January 2018

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Activation of the ribosomal DNA promoter in cells exposed to insulinlike growth factor I.

21 January 2018

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PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

21 January 2018

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The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

21 January 2018

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Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I

21 January 2018

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Insulin-like growth factor I receptor signaling in transformation by src oncogenes

21 January 2018

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Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

21 January 2018

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Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein

21 January 2018

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Association of insulin receptor substrate-1 with integrins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

Isolation of DICE1: a gene frequently affected by LOH and downregulated in lung carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

Co-operation of simian virus 40 T antigen and insulin receptor substrate-1 in protection from apoptosis induced by interleukin-3 withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

Multiple Signals Mediate Proliferation, Differentiation, and Survival from the Granulocyte Colony-stimulating Factor Receptor in Myeloid 32D Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

The IGF-I receptor in cell growth, transformation and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Monocytically Differentiating HL60 Cells Proliferate Rapidly before They Mature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Synthetic alphaVbeta3 antagonists inhibit insulin-like growth factor-I-stimulated smooth muscle cell migration and replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Stimulation of IRS-1-associated phosphatidylinositol 3-kinase and Akt/protein kinase B but not glucose transport by beta1-integrin signaling in rat adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Cross-talk between insulin receptor and integrin alpha5 beta1 signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Insulin-like growth factor I (IGF-I) receptor overexpression abolishes the IGF requirement for differentiation and induces a ligand-dependent transformed phenotype in C2 inducible myoblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Translocation of retinoblastoma protein associated with tumor cell growth inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Constitutive expression of the Id1 gene impairs mouse B cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203854

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203854

1 reference

PubMed ID

11114737

Dimensions Publication ID

31 July 2017

0 references

1 reference

PubMed ID

11114737