(Q28237144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

José Agundez

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

José María Ladero Quesada

20 January 2020

series ordinal

3

object named as

José M Ladero

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Carmen Martínez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

1 January 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

Molecular Diagnosis and Therapy

20 January 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

29-40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16646575%20AND%20SRC:MED&resulttype=core&format=json

Pharmacogenetics - five decades of therapeutic lessons from genetic diversity

20 January 2020

cites work

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21 January 2018

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Haplotype block structure of the cytochrome P450 CYP2C gene cluster on chromosome 10

21 January 2018

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A haplotype map of the human genome

21 January 2018

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Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms

21 January 2018

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The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.

21 January 2018

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Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes

21 January 2018

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Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.

21 January 2018

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Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance

21 January 2018

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Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms

21 January 2018

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Clinical consequences of cytochrome P450 2C9 polymorphisms

21 January 2018

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Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs

21 January 2018

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Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

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Five novel single nucleotide polymorphisms in the CYP2C8 gene, one of which induces a frame-shift.

21 January 2018

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Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population.

21 January 2018

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Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

21 January 2018

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Upstream and coding region CYP2C9 polymorphisms: correlation with warfarin dose and metabolism

21 January 2018

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Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans

21 January 2018

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Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

21 January 2018

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Discovery of new potentially defective alleles of human CYP2C9.

21 January 2018

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Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

21 January 2018

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Identification of a novel variant CYP2C9 allele in Chinese

21 January 2018

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Genetic polymorphisms of CYP2C8 in Japanese population.

21 January 2018

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Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism

21 January 2018

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Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction

21 January 2018

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Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

21 January 2018

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CYP2C9 allelic variants: ethnic distribution and functional significance

21 January 2018

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CYP2C9 allele variants in Chinese hypertension patients and healthy controls

21 January 2018

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Biochemistry and molecular biology of the human CYP2C subfamily

21 January 2018

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Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population

21 January 2018

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The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics

21 January 2018

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Genotyping of cytochrome P450 isoform genes is useful for forensic identification of cadaver

21 January 2018

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Frequency of cytochrome P450 2C9 mutant alleles in a Korean population

21 January 2018

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Genetic polymorphism of CYP2C9 in a Vietnamese Kinh population

21 January 2018

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Lung cancer risk in relation to the CYP2C9*1/CYP2C9*2 genetic polymorphism among African-Americans and Caucasians in Los Angeles County, California

21 January 2018

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Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.

21 January 2018

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Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations

21 January 2018

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Lung cancer risk in relation to the CYP2C9 genetic polymorphism among Caucasians in Los Angeles County

21 January 2018

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21 January 2018

12 December 2020

The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement

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Validation of a new fluorogenic real-time PCR assay for detection of CYP2C9 allelic variants and CYP2C9 allelic distribution in a German population

21 January 2018

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Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population.

21 January 2018

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Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.

21 January 2018

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CYP2C9 genotypes and diclofenac metabolism in Spanish healthy volunteers

21 January 2018

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Association between the CYP2C9 polymorphism and the drug metabolism phenotype

21 January 2018

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Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population

21 January 2018

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Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

21 January 2018

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CYP2C9 genetic variants and losartan oxidation in a Turkish population.

21 January 2018

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Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study

21 January 2018

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Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.

21 January 2018

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CYP2C9 and CYP2C19 genetic polymorphisms: frequencies in the south Indian population.

21 January 2018

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Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy

21 January 2018

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Simulation of the onset of neuromuscular block based on the early oscillations in the arterial plasma concentrations.

21 January 2018

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Analysis of CYP2C9*5 in Caucasian, Oriental and black-African populations

21 January 2018

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Detection of CYP2C9*5 in a white Brazilian subject

21 January 2018

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Amiodarone N-deethylation by CYP2C8 and its variants, CYP2C8*3 and CYP2C8 P404A.

21 January 2018

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Proper controls for SNP studies?

21 January 2018

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CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis

21 January 2018

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Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use

21 January 2018

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Cytochrome P450 gene polymorphism and cancer

21 January 2018

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A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma

21 January 2018

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A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

21 January 2018

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Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk.

21 January 2018

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Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations

21 January 2018

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Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations

21 January 2018

2 references

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21 January 2018

12 December 2020

Allele frequency of CYP2C9 gene polymorphisms in Iran

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12 December 2020

Participation of CYP2C8 in retinoic acid 4-hydroxylation in human hepatic microsomes

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12 December 2020

Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway

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12 December 2020

Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9

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12 December 2020

The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism

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12 December 2020

Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese

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12 December 2020

CYP2C9*3 allelic variant and bleeding complications

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12 December 2020

CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk

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12 December 2020

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

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12 December 2020

Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites

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12 December 2020

Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population

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12 December 2020

Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy.

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12 December 2020

Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment.

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12 December 2020

Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus

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12 December 2020

Evolutionary relationships of human populations on a global scale

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12 December 2020

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

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12 December 2020

Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study

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12 December 2020

Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations

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12 December 2020

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population

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12 December 2020

Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans

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12 December 2020

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes

1 reference

12 December 2020

The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase

1 reference

12 December 2020

Genetic analysis of CYP2C9 polymorphism in a Japanese population

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12 December 2020

Metabolic gene polymorphism frequencies in control populations

1 reference

12 December 2020

Genetic analysis of the human cytochrome P450 CYP2C9 locus

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12 December 2020

Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes

1 reference

12 December 2020

Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes

1 reference

12 December 2020

A single-nucleotide polymorphism tagging set for human drug metabolism and transport

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12 December 2020