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Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases
scientific article (publication date: 2007)
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title
Cyclooxygenase-2, prostaglandin E2, and microglial activation in prion diseases
(English)
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main subject
microglia
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prion protein family
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prostaglandin E2
1 reference
based on heuristic
inferred from title
author
Luisa Minghetti
object named as
Luisa Minghetti
series ordinal
1
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Maurizio Pocchiari
object named as
Maurizio Pocchiari
series ordinal
2
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language of work or name
English
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publication date
2007
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published in
International Review of Neurobiology
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volume
82
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page(s)
265-75
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cites work
Cyclo-oxygenase inhibitors protect against prion-induced neurotoxicity in vitro.
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Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli
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Prostaglandin E2 and microsomal prostaglandin E synthase-2 expression are decreased in the cyclooxygenase-2-deficient mouse brain despite compensatory induction of cyclooxygenase-1 and Ca2+-dependent phospholipase A2.
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COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression
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Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity
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Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease.
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Creutzfeldt-Jakob disease and blood transfusion: results of the UK Transfusion Medicine Epidemiological Review study
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Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease
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COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
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Cyclooxygenase-2 expression during rat neocortical development and in Rett syndrome
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Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions
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Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site
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Cyclooxygenase-2 is highly expressed in microglial-like cells in a murine model of prion disease
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1 reference
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Identifiers
DOI
10.1016/S0074-7742(07)82014-9
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PubMed publication ID
17678966
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ResearchGate publication ID
6160310
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