(Q28240807)

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Daniela Jezova

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Betty Alajajian

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Murat Digicaylioglu

Blood-brain barrier P-glycoprotein function decreases in specific brain regions with aging: a possible role in progressive neurodegeneration

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language of work or name

English

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publication date

August 2011

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published in

Annals of Neurology

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volume

70

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issue

2

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page(s)

194-206

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cites work

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Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[(11)C]verapamil PET.

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Changes in the effectiveness of the blood-brain and blood-spinal cord barriers in experimental allergic encephalomyelitis

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Isolation and culture of microvascular endothelial cells from murine spinal cord.

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Ultrastructure of blood-brain barrier and blood-spinal cord barrier in SOD1 mice modeling ALS.

21 January 2018

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Neuroprotective effects of neurotrophins and melanocortins in spinal cord injury: an experimental study in the rat using pharmacological and morphological approaches.

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Endothelial transcytotic machinery involves supramolecular protein-lipid complexes

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Fluorescence imaging of blood-brain barrier disruption

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Blood‐spinal cord barrier after spinal cord injury: Relation to revascularization and wound healing

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A simple fluorescence technique to stain the plasma membrane of human neutrophils

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A quantitative spatial analysis of the blood-spinal cord barrier. I. Permeability changes after experimental spinal contusion injury.

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Magnetic resonance imaging of blood-spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis.

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Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols.

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Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier

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The blood-brain barrier in vitro: the second decade

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New approaches to in vitro models of blood-brain barrier drug transport.

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Neurovascular unit dysfunction: a vascular component of Alzheimer disease?

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Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

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Pericyte signaling in the neurovascular unit

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Dysfunctional cell-cell signaling in the neurovascular unit as a paradigm for central nervous system disease

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The blood-brain barrier/neurovascular unit in health and disease

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Cell-cell signaling in the neurovascular unit

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Cell biology of the neurovascular unit: implications for drug delivery across the blood-brain barrier

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Signalling within the neurovascular unit in the mammalian retina

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The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems.

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Chronic inflammatory pain and the neurovascular unit: a central role for glia in maintaining BBB integrity?

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Studying the neurovascular unit: an improved blood-brain barrier model

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Brain endothelial cells and the glio-vascular complex

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Use of serotonin immunocytochemistry as a marker of injury severity after experimental spinal trauma in rats

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Blood-spinal cord barrier disruption proximal to a spinal cord transection in the rat: time course and pathways associated with protein leakage

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Vasogenic edema in the injured spinal cord: A method of evaluating the extent of blood-brain barrier alteration to horseradish peroxidase

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Vascular permeability to protein and vasogenic oedema in experimental concussive injuries to the canine spinal cord.

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Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms.

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Immediate damage to the blood-spinal cord barrier due to mechanical trauma.

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Evaluating regional blood spinal cord barrier dysfunction following spinal cord injury using longitudinal dynamic contrast-enhanced MRI.

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Separation of the perivascular basement membrane provides a conduit for inflammatory cells in a mouse spinal cord injury model.

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Immunolocalization of endothelin in the traumatized spinal cord: relationship to blood-spinal cord barrier breakdown

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Intrathecal administration of endothelin-1 in the rat: impact on spinal cord blood flow and the blood-spinal cord barrier

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Role of endothelin in pial artery vasoconstriction and altered responses to vasopressin after brain injury.

21 January 2018

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Mammalian aquaporins: diverse physiological roles and potential clinical significance

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The relationships among the severity of spinal cord injury, motor and somatosensory evoked potentials and spinal cord blood flow

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Traumatic spinal cord injury alters angiogenic factors and TGF-beta1 that may affect vascular recovery

21 January 2018

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Unraveling the riddle of syringomyelia

21 January 2018

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Neurosurgical considerations in posttraumatic syringomyelia

21 January 2018

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Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the Am

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Genetics of motor neuron disorders: new insights into pathogenic mechanisms

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The blood-brain barrier in health and chronic neurodegenerative disorders

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Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis.

21 January 2018

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IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis.

21 January 2018

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Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS

21 January 2018

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ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

21 January 2018

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Impaired blood-brain and blood-spinal cord barriers in mutant SOD1-linked ALS rat.

21 January 2018

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Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS.

21 January 2018

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A possible haemodynamic mechanism for amyotrophic lateral sclerosis.

21 January 2018

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No evidence of microbleeds in ALS patients at 7 Tesla MRI.

21 January 2018

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Reduction of circulating endothelial cells in peripheral blood of ALS patients

21 January 2018

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Early radiation-induced endothelial cell loss and blood-spinal cord barrier breakdown in the rat spinal cord

21 January 2018

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Intercellular adhesion molecule-1 and blood-spinal cord barrier disruption in central nervous system radiation injury

21 January 2018

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Upregulation of vascular endothelial growth factor is associated with radiation-induced blood-spinal cord barrier breakdown.

21 January 2018

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Lymphocyte migration into the central nervous system: implication of ICAM-1 signalling at the blood-brain barrier

21 January 2018

1 reference

Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1).

21 January 2018

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Effector functions of antiaquaporin-4 autoantibodies in neuromyelitis optica

21 January 2018

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Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain.

21 January 2018

1 reference

Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis

21 January 2018

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MRI-based monitoring of inflammation and tissue damage in acute and chronic relapsing EAE.

21 January 2018

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Molecular mechanisms involved in T cell migration across the blood-brain barrier.

21 January 2018

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The spectrum of neuromyelitis optica

21 January 2018

1 reference

Neuromyelitis optica pathogenesis and aquaporin 4

21 January 2018

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Blood brain barrier in hypoxic-ischemic conditions

21 January 2018

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Blood flow and vascular permeability during motor dysfunction in a rabbit model of spinal cord ischemia

21 January 2018

1 reference

The temporal profile of the reaction of microglia, astrocytes, and macrophages in the delayed onset paraplegia after transient spinal cord ischemia in rabbits

21 January 2018

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CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain

21 January 2018

1 reference

T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity.

21 January 2018

1 reference

Expression of CCR2 in Both Resident and Bone Marrow-Derived Microglia Plays a Critical Role in Neuropathic Pain

21 January 2018

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Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier

21 January 2018

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Spinal cord repair strategies: why do they work?

21 January 2018

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Spinal cord injury: time to move?

21 January 2018

1 reference

Repeated topical application of growth hormone attenuates blood-spinal cord barrier permeability and edema formation following spinal cord injury: an experimental study in the rat using Evans blue, ([125])I-sodium and lanthanum tracers.

21 January 2018

1 reference

Magnesium sulfate treatment in experimental spinal cord injury: emphasis on vascular changes and early clinical results.

21 January 2018

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Tamoxifen attenuates inflammatory-mediated damage and improves functional outcome after spinal cord injury in rats.

21 January 2018

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Combination of dexamethasone and aminoguanidine reduces secondary damage in compression spinal cord injury

21 January 2018

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Effect of VEGF treatment on the blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced magnetic resonance imaging

21 January 2018

1 reference

VEGF increases blood-brain barrier permeability to Evans blue dye and tetanus toxin fragment C but not adeno-associated virus in ALS mice

21 January 2018

1 reference

Beneficial effect of erythropoietin on experimental allergic encephalomyelitis.

21 January 2018

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Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury

21 January 2018

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A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair

21 January 2018

1 reference

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

21 January 2018

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Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis.

21 January 2018

1 reference

Novel multifunctional polyethylene glycol-transactivating-transduction protein-modified liposomes cross the blood-spinal cord barrier after spinal cord injury

21 January 2018

1 reference

Nanowired-drug delivery enhances neuroprotective efficacy of compounds and reduces spinal cord edema formation and improves functional outcome following spinal cord injury in the rat.

21 January 2018

1 reference

PEGlated magnetic polymeric liposome anchored with TAT for delivery of drugs across the blood-spinal cord barrier

21 January 2018

1 reference

Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging

21 January 2018

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Nanotechnology in ophthalmology

21 January 2018

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Nanomedicine in ophthalmology: the new frontier

21 January 2018

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Silicon dioxide nanoparticles (SiO2, 40-50 nm) exacerbate pathophysiology of traumatic spinal cord injury and deteriorate functional outcome in the rat. An experimental study using pharmacological and morphological approaches.

21 January 2018

1 reference