(Q36506367)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

review article

1 reference

title

Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

3

Melanie Greter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Ingo Bechmann

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

publication date

14 June 2006

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Medicine

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

532-543

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00109-006-0065-1

30 January 2020

exact match

0 references

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12 December 2020

Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis

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Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

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12 December 2020

Dendritic cells: specialized and regulated antigen processing machines

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12 December 2020

Characterization and distribution of phagocytic macrophages in multiple sclerosis plaques

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12 December 2020

Hyperinducibility of Ia antigen on astrocytes correlates with strain-specific susceptibility to experimental autoimmune encephalomyelitis

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12 December 2020

Are astrocytes central players in the pathophysiology of multiple sclerosis?

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12 December 2020

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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12 December 2020

Immune function of the blood-brain barrier: incomplete presentation of protein (auto-)antigens by rat brain microvascular endothelium in vitro

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Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

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12 December 2020

Local enhancement of major histocompatibility complex (MHC) class I and II expression and cell infiltration in experimental allergic encephalomyelitis around axotomized motor neurons

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12 December 2020

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

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12 December 2020

Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS.

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12 December 2020

HLA class II molecules (HLA-DR, -DP, -DQ) on cells in the human CNS studied in situ and in vitro

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12 December 2020

Initiation of immune responses in brain is promoted by local dendritic cells.

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12 December 2020

Presence of B7--2 (CD86) and lack of B7--1 (CD(80) on myelin phagocytosing MHC-II-positive rat microglia is associated with nondestructive immunity in vivo.

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12 December 2020

Microglia in degenerative neurological disease.

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12 December 2020

Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system

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12 December 2020

Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation

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12 December 2020

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

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12 December 2020

Myelin basic protein in CSF as indicator of disease activity in multiple sclerosis

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12 December 2020

Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial-derived cytokine IL-1.

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12 December 2020

Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs.

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12 December 2020

Immune function of astrocytes

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12 December 2020

Mature microglia resemble immature antigen-presenting cells

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12 December 2020

Defining antigen-dependent stages of T cell migration from the blood to the central nervous system parenchyma.

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12 December 2020

Systemic Immune Deviation in the Brain That Does Not Depend on the Integrity of the Blood-Brain Barrier

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12 December 2020

Lymphocyte targeting of the brain in adoptive transfer cryolesion-EAE.

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12 December 2020

Peripheral T cell tolerance

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12 December 2020

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier.

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12 December 2020

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

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12 December 2020

Multiple sclerosis: presence of lymphatic capillaries and lymphoid tissue in the brain and spinal cord

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12 December 2020

Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules.

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12 December 2020

Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

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12 December 2020

Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations.

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12 December 2020

Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: membrane currents

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12 December 2020

Brain-immune connection: immuno-regulatory properties of CNS-resident cells

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12 December 2020

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

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12 December 2020

The role of CD8(+) T cells in multiple sclerosis and its animal models

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12 December 2020

Heterogeneity of microglial and perivascular cell populations: insights gained from the facial nucleus paradigm

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12 December 2020

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia.

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12 December 2020

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

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12 December 2020

Turnover of rat brain perivascular cells.

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12 December 2020

Role of autoreactive CD8+ T cells in organ-specific autoimmune diseases: insight from transgenic mouse models

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12 December 2020

The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis.

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12 December 2020

Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease

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12 December 2020

Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions.

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12 December 2020

MRI aspects of the "inflammatory phase" of multiple sclerosis.

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12 December 2020

Immune function of microglia

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12 December 2020

Basic principles of immunological surveillance of the normal central nervous system

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12 December 2020

Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras

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12 December 2020

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

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12 December 2020

Failed central nervous system regeneration: a downside of immune privilege?

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12 December 2020

Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts

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12 December 2020

Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy.

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12 December 2020

Bacillus Calmette-Guérin sequestered in the brain parenchyma escapes immune recognition.

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12 December 2020

Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells

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12 December 2020

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

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12 December 2020

How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes.

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12 December 2020

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

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12 December 2020

Immunopathogenesis of multiple sclerosis: MBP and beyond

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12 December 2020

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

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12 December 2020

Role of cervical lymph nodes in autoimmune encephalomyelitis in the Lewis rat.

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12 December 2020

Dissection of an inflammatory process induced by CD8+ T cells

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12 December 2020

Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells.

1 reference

12 December 2020

Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells

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12 December 2020

Studies on the problem of corneal homografts

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12 December 2020

H. polygyrus: B7-independence of the secondary type 2 response

1 reference

12 December 2020

The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system.

1 reference

12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

12 December 2020

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

12 December 2020

IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells

1 reference

12 December 2020

Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

1 reference

12 December 2020

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

12 December 2020

Immunologically privileged sites

1 reference

12 December 2020

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

1 reference

12 December 2020

The role of T-cell-mediated mechanisms in virus infections of the nervous system

1 reference

12 December 2020

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

1 reference

12 December 2020

Differentiated Th1 autoreactive effector cells can induce experimental autoimmune encephalomyelitis in the absence of IL-12 and CD40/CD40L interactions

1 reference

12 December 2020

IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide

1 reference

12 December 2020

Astrocytes and central nervous system endothelial cells do not express B7-1 (CD80) or B7-2 (CD86) immunoreactivity during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats.

1 reference

12 December 2020

Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells.

1 reference

12 December 2020

Autoimmune intervention by CD154 blockade prevents T cell retention and effector function in the target organ

1 reference

12 December 2020

Vasoactive intestinal polypeptide inhibits the expression of the MHC class II antigens on astrocytes

1 reference

12 December 2020

Apoptosis of inflammatory cells in immune control of the nervous system: role of glia

1 reference

12 December 2020

IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo.

1 reference

12 December 2020

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

1 reference

12 December 2020

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1 reference

12 December 2020

The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis

1 reference

12 December 2020

Targeting of adoptively transferred experimental allergic encephalitis lesion at the sites of wallerian degeneration.

1 reference

12 December 2020

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

12 December 2020

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

12 December 2020

Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis.

1 reference

12 December 2020

Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages.

1 reference

12 December 2020

CD95-CD95L: can the brain learn from the immune system?

1 reference

12 December 2020

T cells in the central nervous system: the delicate balance between viral clearance and disease

1 reference

12 December 2020

A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation.

1 reference

12 December 2020

Activation of adult human derived microglia by myelin phagocytosis in vitro

1 reference

12 December 2020

Functional activation of myelin-specific T cells by virus-induced molecular mimicry

1 reference

12 December 2020

Migration of Hematogenous Cells Through the Blood-Brain Barrier and the Initiation of CNS Inflammation

1 reference

12 December 2020

Astrocytic factors deactivate antigen presenting cells that invade the central nervous system.

1 reference

12 December 2020

T cell mediated neuroprotection is a physiological response to central nervous system insults

1 reference

12 December 2020

Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation

1 reference

12 December 2020

Inflammation and atrophy in multiple sclerosis: MRI associations with disease course

1 reference

12 December 2020

Requirement for Θ-Bearing Cells in Lymphocytic Choriomeningitis Virus-induced Central Nervous System Disease

1 reference

12 December 2020

Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain.

1 reference

12 December 2020

Multiple sclerosis trial designs for the 21st century: building on recent lessons

1 reference

12 December 2020

Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

1 reference

12 December 2020

Mouse resident microglia: isolation and characterization of immunoregulatory properties with naïve CD4+ and CD8+ T-cells.

1 reference

12 December 2020

In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology.

1 reference

12 December 2020

Investigation on the expression of major histocompatibility complex class II and cytokines and detection of HIV-1 DNA within brains of asymptomatic and symptomatic HIV-1-positive patients

1 reference

12 December 2020

The use of magnetic resonance imaging in the diagnosis and long-term management of multiple sclerosis

1 reference

12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

12 December 2020

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

1 reference

12 December 2020

Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation.

1 reference

12 December 2020

Microglia induce CD4 T lymphocyte final effector function and death

1 reference

12 December 2020

Ia expression and antigen presentation by glia: strain and cell type-specific differences among rat astrocytes and microglia.

1 reference

12 December 2020

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

12 December 2020

Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes

1 reference

12 December 2020

EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses

1 reference

12 December 2020

Regulation and function of class II major histocompatibility complex, CD40, and B7 expression in macrophages and microglia: Implications in neurological diseases

1 reference

12 December 2020

CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS

1 reference

12 December 2020

Anti-inflammatory cytokines: expression and action in the brain

1 reference

12 December 2020

Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence.

1 reference

12 December 2020

IL-23: a cytokine that acts on memory T cells

1 reference

12 December 2020

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

1 reference

12 December 2020

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

1 reference

12 December 2020

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

1 reference

12 December 2020

10.1007/S00109-006-0065-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16773356%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference