(Q74307292)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12067291%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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title

Immunopathogenesis of multiple sclerosis: MBP and beyond (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12067291%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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E Meinl

1

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10 November 2019

R Hohlfeld

series ordinal

2

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10 November 2019

publication date

1 June 2002

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Clinical and Experimental Immunology

10 November 2019

published in

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10 November 2019

volume

128

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10 November 2019

issue

3

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10 November 2019

page(s)

395-397

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In healthy primates, circulating autoreactive T cells mediate autoimmune disease

10 November 2019

cites work

1 reference

12 December 2020

Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

1 reference

12 December 2020

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

1 reference

12 December 2020

Autoreactive CD8+ T-cell responses to human myelin protein-derived peptides

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12 December 2020

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

1 reference

12 December 2020

Assessment of animal models for MS and demyelinating disease in the design of rational therapy

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12 December 2020

Contribution of individual amino acids within MHC molecule or antigenic peptide to TCR ligand potency

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12 December 2020

Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence.

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12 December 2020

Preferential expansion of autoreactive T lymphocytes from the memory T-cell pool by IL-7

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12 December 2020

A phase I trial of solubilized DR2:MBP84-102 (AG284) in multiple sclerosis

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12 December 2020

Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex

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12 December 2020

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

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12 December 2020

The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis.

1 reference

12 December 2020

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

1 reference

12 December 2020

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

12 December 2020

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

1 reference

12 December 2020

T-cell reactivity to multiple myelin antigens in multiple sclerosis patients and healthy controls

1 reference

12 December 2020

Anergy induction by dimeric TCR ligands

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12 December 2020

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

12 December 2020

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

1 reference

12 December 2020

CD4+CD28- costimulation-independent T cells in multiple sclerosis

1 reference

12 December 2020

Diversity and dynamics of the T-cell response to MBP in DR2+ve individuals

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12 December 2020

Isolation of myelin basic protein-reactive T-cell lines from normal human blood

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12 December 2020

T cells responsive to myelin basic protein in patients with multiple sclerosis

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12 December 2020

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1 reference

12 December 2020

Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors.

1 reference

12 December 2020

A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis

1 reference

12 December 2020

Myelin basic protein-specific T lymphocytes in multiple sclerosis and controls: precursor frequency, fine specificity, and cytotoxicity

1 reference

12 December 2020

Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients

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12 December 2020

MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination

1 reference

12 December 2020

Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones

1 reference

12 December 2020

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

1 reference

12 December 2020

Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide

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12 December 2020

Activation of a myelin basic protein-specific human T cell clone by antigen-presenting cells from rhesus monkeys

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12 December 2020

Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques

1 reference

12 December 2020

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone

1 reference

12 December 2020

Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives

1 reference

12 December 2020

Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells

1 reference

12 December 2020

Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation

1 reference

12 December 2020

Immunity to T cell receptor peptides in multiple sclerosis. III. Preferential immunogenicity of complementarity-determining region 2 peptides from disease-associated T cell receptor BV genes

1 reference

12 December 2020

Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein

1 reference

12 December 2020

Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein

1 reference

12 December 2020

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

1 reference

12 December 2020

10.1046/J.1365-2249.2002.01879.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12067291%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

1 reference