(Q28243737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

0 references

0 references

6

1 reference

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8 February 2020

14

Hugo A Katus

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

12

Philip Raake

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Sven T Pleger

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Changguang Shan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jan Ksienzyk

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Raffi Bekeredjian

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Peter Boekstegers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Stefanie Schinkel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Barbara Leuchs

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jochen Ludwig

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Gang Qiu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Christophe Weber

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Walter J Koch

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Oliver J Müller

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Patrick Most

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

1 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

8 February 2020

published in

1 reference

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8 February 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

92

1 reference

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8 February 2020

page(s)

92ra64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

S100A1: Structure, Function, and Therapeutic Potential

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

The myocardial protein S100A1 plays a role in the maintenance of normal gene expression in the adult heart

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

20 March 2017

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Cardiac excitation-contraction coupling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

S100A1: a regulator of myocardial contractility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Heart disease and stroke statistics--2011 update: a report from the American Heart Association

20 March 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Clinical practice. Systolic heart failure.

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Large animal models of heart failure: a critical link in the translation of basic science to clinical practice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Targeting myocardial beta-adrenergic receptor signaling and calcium cycling for heart failure gene therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Principles of genetic murine models for cardiac disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Review of current and investigational pharmacologic agents for acute heart failure syndromes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Energy metabolism in heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Cardiac energy metabolism homeostasis: role of cytosolic calcium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Inotropic therapy for heart failure: an evidence-based approach.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Functional consequences of altering myocardial adrenergic receptor signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

The epidemiology of heart failure: the Framingham Study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Effect of spironolactone on left ventricular ejection fraction and volumes in patients with class I or II heart failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Ca2+ signaling in mouse cardiomyocytes with ablated S100A1 protein.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Detection of coronary artery stenosis with power Doppler imaging

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Sealing the leak, healing the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Method for isolation of human ventricular myocytes from single endocardial and epicardial biopsies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095769

Selective Pressure-Regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia

27 November 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002097

Antiremodeling effects on the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure

21 January 2018

1 reference

12 December 2020

Effects of long-term enalapril therapy on cardiac structure and function in patients with left ventricular dysfunction. Results of the SOLVD echocardiography substudy

1 reference

12 December 2020

Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy : the randomized evaluation of strategies for left ventricular dysfunction pilot study

1 reference

12 December 2020

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure

1 reference

12 December 2020

Functional and bioenergetic consequences of postinfarction left ventricular remodeling in a new porcine model. MRI and 31 P-MRS study

1 reference

12 December 2020

Transgenic rabbits expressing mutant essential light chain do not develop hypertrophic cardiomyopathy

1 reference

12 December 2020

10.1126/SCITRANSLMED.3002097

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21775667%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2 references