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Asymmetric and symmetric stem-cell divisions in development and cancer
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title
Asymmetric and symmetric stem-cell divisions in development and cancer
(English)
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author
Judith Kimble
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2
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Sean J. Morrison
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Sean J Morrison
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1
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language of work or name
English
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publication date
29 June 2006
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published in
Nature
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volume
441
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page(s)
1068-74
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issue
7097
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cites work
Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cells, asymmetric division and cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric cell division: fly neuroblast meets worm zygote
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling in stem cell niches: lessons from the Drosophila germline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the control of germ cell development in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The purification and characterization of fetal liver hematopoietic stem cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric cell divisions promote stratification and differentiation of mammalian skin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric cell division and axis formation in the embryo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of asymmetry and segregation of germ-line granules in early C. elegans embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PIE-1 protein and germline specification in C. elegans embryos.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A niche maintaining germ line stem cells in the Drosophila ovary
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cells find their niche
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cell niche: structure and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dpp Signaling Silences bam Transcription Directly to Establish Asymmetric Divisions of Germline Stem Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline stem cells anchored by adherens junctions in the Drosophila ovary niches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric cell division in C. elegans: cortical polarity and spindle positioning
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extrinsic cues orient the cell division axis in Drosophila embryonic neuroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila ovarian and testis stem cell niches: similar somatic stem cells and signals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
A beta-catenin identified by functional rather than sequence criteria and its role in Wnt/MAPK signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
Cki-1 links cell division and cell fate acquisition in the C. elegans somatic gonad
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Symmetric versus asymmetric cell division during neurogenesis in the developing vertebrate central nervous system
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spectrosomes and fusomes anchor mitotic spindles during asymmetric germ cell divisions and facilitate the formation of a polarized microtubule array for oocyte specification in Drosophila
1 reference
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regeneration of male germline stem cells by spermatogonial dedifferentiation in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular analyses of the mitotic region in the Caenorhabditis elegans adult germ line
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development.
1 reference
stated in
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stroke transiently increases subventricular zone cell division from asymmetric to symmetric and increases neuronal differentiation in the adult rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A self-renewing multipotential stem cell in embryonic rat cerebral cortex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of deletion mutations and three new genes at the familial polyposis locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of the familial adenomatous polyposis coli gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of FAP locus genes from chromosome 5q21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of Hugl-1 is strongly reduced in malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant activation of notch signaling in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer
1 reference
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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inferred from DOI database lookup
p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stem cells, cancer, and cancer stem cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Applying the principles of stem-cell biology to cancer
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stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNATURE04956
retrieved
7 January 2021
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Identifiers
DOI
10.1038/NATURE04956
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stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1210011
Dimensions Publication ID
1040722466
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OpenCitations bibliographic resource ID
1210011
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1210011
PubMed ID
16810241
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1210011
ResearchGate publication ID
6975061
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Springer Nature article ID
10.1038/nature04956
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