(Q28251734)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

review article

1 reference

title

The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

0 references

0 references

1

1 reference

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8 January 2020

Thomas C Gent

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sarah L. Freeman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Neil Foster

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Richard Barrett-Jolley

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Ali Mobasheri

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Abigail Clutterbuck

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Pat Harris

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

29 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

published in

The Veterinary Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

1

1 reference

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8 January 2020

page(s)

10-24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

Phenyl N-tert-butylnitrone down-regulates interleukin-1 beta-stimulated matrix metalloproteinase-13 gene expression in human chondrocytes: suppression of c-Jun NH2-terminal kinase, p38-mitogen-activated protein kinase and activating protein-1

8 January 2020

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Inhibition of tumor necrosis factor alpha-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways

7 January 2021

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Mediation of interleukin-1beta-induced transforming growth factor beta1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: possible cooperation with activator protein 1.

7 January 2021

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Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis

7 January 2021

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Leukaemia inhibitory factor (LIF) suppresses proteoglycan synthesis in porcine and caprine cartilage explants

7 January 2021

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Synovial tissue inflammation in early and late osteoarthritis

7 January 2021

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Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

7 January 2021

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Induction of intra-articular tumour necrosis factor during acute inflammatory responses in equine arthritis

7 January 2021

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Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

7 January 2021

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The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

7 January 2021

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Matrix metalloproteinase activity in equine synovial fluid: influence of age, osteoarthritis, and osteochondrosis

7 January 2021

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Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid

7 January 2021

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Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts

7 January 2021

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Substance P in the synovial membrane and fluid of the equine middle carpal joint

7 January 2021

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Leukaemia inhibitory factor stimulates proteoglycan resorption in porcine articular cartilage

7 January 2021

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Leukemia inhibitory factor induces leukocyte infiltration and cartilage proteoglycan degradation in goat joints.

7 January 2021

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Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan

7 January 2021

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Interleukin-18 induces the production of vascular endothelial growth factor (VEGF) in rheumatoid arthritis synovial fibroblasts via AP-1-dependent pathways

7 January 2021

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The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation

7 January 2021

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Synergistic effect of IGF-1 and OP-1 on matrix formation by normal and OA chondrocytes cultured in alginate beads

7 January 2021

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Matrix metalloproteinases 2 and 9 in equine synovial fluids

7 January 2021

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Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells.

7 January 2021

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Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis

7 January 2021

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Growth factor impact on articular cartilage subpopulations

7 January 2021

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Expression of neutrophil activation markers and neutrophil adhesion to chondrocytes in rheumatoid arthritis patients: relationship with disease activity

7 January 2021

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Interleukin-4 but not interleukin-10 inhibits the production of leukemia inhibitory factor by rheumatoid synovium and synoviocytes

7 January 2021

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Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease

7 January 2021

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The significance of vasoactive intestinal peptide in immunomodulation

7 January 2021

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Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat.

7 January 2021

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Aggrecan, aging and assembly in articular cartilage.

7 January 2021

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Experimental arthritis induced by continuous infusion of IL-8 into rabbit knee joints

7 January 2021

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Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes

7 January 2021

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The effect of synovial tissue on the breakdown of articular cartilage in organ culture

7 January 2021

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MR features of osteoarthritis of the knee

7 January 2021

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Synovial thickening detected by MR imaging in osteoarthritis of the knee confirmed by biopsy as synovitis.

7 January 2021

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Vasoactive intestinal peptide induces cyclooxygenase-2 expression through nuclear factor-kappaB in human prostate cell lines Differential time-dependent responses in cancer progression

7 January 2021

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Inflammatory status and cartilage regenerative potential of synovial fibroblasts from patients with osteoarthritis and chondropathy.

7 January 2021

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IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

7 January 2021

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Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis

7 January 2021

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Induction of antimicrobial pathways during early-phase immune response to Salmonella spp. in murine macrophages: gamma interferon (IFN-gamma) and upregulation of IFN-gamma receptor alpha expression are required for NADPH phagocytic oxidase gp91-stim

7 January 2021

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VIP Inhibits Porphyromonas gingivalis LPS-induced immune responses in human monocytes

7 January 2021

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Inhibition of IFN-gamma-stimulated proinflammatory cytokines by vasoactive intestinal peptide (VIP) correlates with increased survival of Salmonella enterica serovar typhimurium phoP in murine macrophages.

7 January 2021

1 reference

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Vasoactive intestinal peptide (VIP) prevents killing of virulent and phoP mutant Salmonella typhimurium by inhibiting IFN-gamma stimulated NADPH oxidative pathways in murine macrophages.

7 January 2021

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Pivotal advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages.

7 January 2021

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Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.

7 January 2021

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Vasoactive intestinal peptide family as a therapeutic target for Parkinson's disease.

7 January 2021

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Tumour necrosis factor alpha stimulates nitric oxide production more potently than interleukin-1beta in porcine articular chondrocytes.

7 January 2021

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A proinflammatory role for IL-18 in rheumatoid arthritis

7 January 2021

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VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

A role for the C-terminal fragment of substance P,SP7-11 in the pathogenesis of arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

A metabolite of substance P, SP7-11 is involved in the pathogenesis of inflammatory joint disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Transforming growth factor-? inhibition of interleukin-1 activity involves down-regulation of interleukin-1 receptors on chondrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model

7 January 2021

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Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes

7 January 2021

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Pharmaceutical and nutraceutical management of canine osteoarthritis: present and future perspectives.

7 January 2021

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Effect of calcitonin gene-related peptide, neuropeptide Y, substance P, and vasoactive intestinal peptide on interleukin-1beta, interleukin-6 and tumor necrosis factor-alpha production by peripheral whole blood cells from rheumatoid arthritis and os

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

IL-17, IL-1beta and TNF-alpha stimulate VEGF production by dedifferentiated chondrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Expression and distribution of transforming growth factor-beta isoforms and their signaling receptors in growing human bone

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Effect of transforming growth factor-beta and platelet-derived growth factor-BB on articular cartilage in rats

7 January 2021

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Intra-articular variation of synovial changes in knee arthritis: biopsy study comparing changes in patellofemoral synovium and the medial tibiofemoral synovium

7 January 2021

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Inhibitory Effects of Insulin-like Growth Factor-1 and Osteogenic Protein-1 on Fibronectin Fragment- and Interleukin-1β-stimulated Matrix Metalloproteinase-13 Expression in Human Chondrocytes

7 January 2021

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Morphology and functional roles of synoviocytes in the joint

7 January 2021

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Equine synovial villi: distinctive structural organization of vasculature and novel nerve endings

7 January 2021

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Effects of interleukin-6 on proliferation and proteoglycan metabolism in articular chondrocyte cultures

7 January 2021

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Effect of IL-13 on cytokines, cytokine receptors and inhibitors on human osteoarthritis synovium and synovial fibroblasts.

7 January 2021

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Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis.

7 January 2021

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Autocrine or paracrine inflammatory actions of corticotropin-releasing hormone in vivo.

7 January 2021

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Concentrations of substance P and prostaglandin E2 in synovial fluid of normal and abnormal joints of horses

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

IL-1- and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids

7 January 2021

1 reference

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Acute inflammation in the rat knee joint attenuates sympathetic vasoconstriction but enhances neuropeptide-mediated vasodilatation assessed by laser Doppler perfusion imaging

7 January 2021

1 reference

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Pharmacology of drugs used to treat osteoarthritis in veterinary practice

7 January 2021

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Neutrophil attractant/activation protein-1 (NAP-1 [interleukin-8]).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Stimulation of interleukin-6 production by corticotropin-releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Combined Effects of IL-12 and IL-18 on the Induction of Collagen-Induced Arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Intraneuronal substance P contributes to the severity of experimental arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Arthroscopic and immunohistologic characterization of knee joint synovitis in osteoarthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes

7 January 2021

1 reference

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Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity

7 January 2021

1 reference

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Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Insulin-like growth factor I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Substance P and arthritis: analysis of plasma and synovial fluid levels.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Cytokines and their role in the pathophysiology of osteoarthritis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Neuropeptide substance P stimulates the formation of osteoclasts via synovial fibroblastic cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

The ultrastructural localization of fibronectin in the lining layer of rheumatoid arthritis synovium: The synthesis of fibronectin by type B lining cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Effects of interleukin-1 beta on insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Vasoactive intestinal peptide (VIP) is a modulator of joint pain in a rat model of osteoarthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Quantitative analysis of voltage-gated potassium currents from primary equine (Equus caballus) and elephant (Loxodonta africana) articular chondrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

The distribution of cartilage oligomeric matrix protein (COMP) in equine carpal articular cartilage and its variation with exercise and cartilage deterioration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Growth factor regulation of human growth plate chondrocyte proliferation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Induction of nitric oxide synthase in human chondrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Il-4 and IL-13, but not IL-10, protect human synoviocytes from apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Influence of pro-inflammatory (IL-1 alpha, IL-6, TNF-alpha, IFN-gamma) and anti-inflammatory (IL-4) cytokines on chondrocyte function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

[Differential diagnosis of synovitis. Correlation of arthroscopic-biopsy to clinical findings]

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

TNFα suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF‐κB signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin 4 inhibits murine osteoclast formation in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Enhancing effect of corticotropin-releasing neurohormone on the production of interleukin-1 and interleukin-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Gross, histologic, and gene expression characteristics of osteoarthritic articular cartilage of the metacarpal condyle of horses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Cellular sources of proteolytic enzymes in equine joints

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Effects of equine recombinant interleukin-1alpha and interleukin-1beta on proteoglycan metabolism and prostaglandin E2 synthesis in equine articular cartilage explants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Deactivation of macrophages by transforming growth factor-β

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

In vivo effects of interleukin-1 on articular cartilage. Prolongation of proteoglycan metabolic disturbances in old mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Induction of cytokine expression by leukemia inhibitory factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Spontaneous production of nitric oxide (NO), prostaglandin (PGE2) and neutral metalloproteinases (NMPs) in media of explant cultures of equine synovial membrane and articular cartilage from normal and osteoarthritic joints

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Roles of aggrecan, a large chondroitin sulfate proteoglycan, in cartilage structure and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Elevated levels of corticotrophin-releasing factor binding protein in the blood of patients suffering from arthritis and septicaemia and the presence of novel ligands in synovial fluid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin 8 modulates interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha release from normal human mononuclear cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

Interleukin-1-like activity in synovial fluids and sera of horses with arthritis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Characterisation of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Modulation by soluble factors of gelatinase activities released by osteoblastic cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2007.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.TVJL.2007.08.013

2 references

Consolidated OpenCitations Corpus – April 2017

2755689

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17911037%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2755689

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2755689