(Q28254941)

1

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Fabienne Jäggi

2

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Sandra P Widjaja

3

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Gerhard Christofori

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

29 September 2006

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published in

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volume

281

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issue

39

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page(s)

29201-12

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cites work

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Cell signaling by receptor tyrosine kinases

21 January 2018

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Common and distinct elements in cellular signaling via EGF and FGF receptors

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Negative receptor signalling

21 January 2018

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Split personalities: the agonistic antagonist Sprouty

21 January 2018

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Modulation of signalling by Sprouty: a developing story

21 January 2018

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Sprouty: how does the branch manager work?

21 January 2018

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Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.

21 January 2018

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sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

21 January 2018

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Sprouty, an intracellular inhibitor of Ras signaling.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain

21 January 2018

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Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

21 January 2018

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Cloning and expression pattern of a mouse homologue of drosophila sprouty in the mouse embryo

21 January 2018

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Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

21 January 2018

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Inhibition of angiogenesis by a mouse sprouty protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.

21 January 2018

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Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

21 January 2018

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Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase

21 January 2018

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Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

21 January 2018

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The C terminus of sprouty is important for modulation of cellular migration and proliferation.

21 January 2018

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Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2.

21 January 2018

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The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Distinct requirements for the Sprouty domain for functional activity of Spred proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Evidence for direct interaction between Sprouty and Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Human SPRY2 inhibits FGF2 signalling by a secreted factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolae and intracellular trafficking of cholesterol

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-1 in oncogenic transformation, cancer, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-1 interacts directly with dynamin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Epithelial growth factor-induced phosphorylation of caveolin 1 at tyrosine 14 stimulates caveolae formation in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Visualization of caveolin-1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras. The subcellular distribution of caveolin-1 is modulated by cell-cell contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Multiple functions of caveolin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

21 January 2018

The caveolin proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603921200