(Q35790325)

10 August 2017

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title

Modulation of signalling by Sprouty: a developing story (English)

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10 August 2017

2

Dafna Bar-Sagi

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10 August 2017

Hong Joo Kim

1

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10 August 2017

1 June 2004

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Nature Reviews Molecular Cell Biology

10 August 2017

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10 August 2017

5

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10 August 2017

6

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10 August 2017

441-450

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https://scigraph.springernature.com/pub.10.1038/nrm1400

10 August 2017

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cites work

Feedback control of intercellular signalling in development

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sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

31 March 2020

1 reference

Cloning and expression pattern of a mouse homologue of drosophila sprouty in the mouse embryo.

31 March 2020

1 reference

Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: an FGF8-inducible member of a family of intracellular FGF antagonists.

31 March 2020

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Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning

31 March 2020

1 reference

Spred is a Sprouty-related suppressor of Ras signalling

31 March 2020

1 reference

The molecular basis of lung morphogenesis

31 March 2020

1 reference

branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching

31 March 2020

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Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis

31 March 2020

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Expression of Sprouty genes 1, 2 and 4 during mouse organogenesis

31 March 2020

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Do lung remodeling, repair, and regeneration recapitulate respiratory ontogeny?

31 March 2020

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Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling.

31 March 2020

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Sprouty, an intracellular inhibitor of Ras signaling.

31 March 2020

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Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

31 March 2020

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ERK pathway positively regulates the expression of Sprouty genes

31 March 2020

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Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation

31 March 2020

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Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis

31 March 2020

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The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development

31 March 2020

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hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl

31 March 2020

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Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

31 March 2020

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Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain

31 March 2020

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The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes

31 March 2020

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The C terminus of sprouty is important for modulation of cellular migration and proliferation.

31 March 2020

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Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

31 March 2020

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Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

31 March 2020

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Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.

31 March 2020

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Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

31 March 2020

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Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

31 March 2020

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mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins

31 March 2020

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The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

31 March 2020

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Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

31 March 2020

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Cbl: many adaptations to regulate protein tyrosine kinases

31 March 2020

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Evidence for direct interaction between Sprouty and Cbl

31 March 2020

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Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

31 March 2020

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Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

31 March 2020

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Timing of cyclin D1 expression within G1 phase is controlled by Rho.

31 March 2020

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

31 March 2020

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Regulation of receptor tyrosine kinase signaling by endocytic trafficking

31 March 2020

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

31 March 2020

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FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

31 March 2020

1 reference

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

31 March 2020

1 reference

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

31 March 2020

1 reference

Fibroblast growth factor receptors: lessons from the genes

31 March 2020

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Inositol trisphosphate and calcium signalling

31 March 2020

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Genetic control of branching morphogenesis

31 March 2020

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The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension

31 March 2020

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breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells

31 March 2020

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Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system

31 March 2020

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Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.

31 March 2020

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Temporal effects of Sprouty on lung morphogenesis.

31 March 2020

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Molecular mechanisms of vasculogenesis and embryonic angiogenesis

31 March 2020

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Signaling vascular morphogenesis and maintenance

31 March 2020

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Inhibition of angiogenesis by a mouse sprouty protein

31 March 2020

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Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty

31 March 2020

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A Drosophila gene regulated by rough and glass shows similarity to ena and VASP.

31 March 2020

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MAP kinase modules: many roads home.

31 March 2020

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Activation of Ras and other signaling pathways by receptor tyrosine kinases

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1400

1 reference

release_rvvqg2ociree7inoz7chjodf4q

10 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rvvqg2ociree7inoz7chjodf4q

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

15173823

1 reference

PubMed ID

15173823