(Q28257072)

4

object named as

Chad A Shaw

0 references

Huda Zoghbi

object named as

Huda Y Zoghbi

6

0 references

author name string

Caleigh Mandel-Brehm

2

0 references

Christopher M McGraw

3

0 references

Bryan E McGill

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

5

0 references

language of work or name

English

0 references

publication date

8 January 2012

0 references

published in

Nature Genetics

0 references

volume

44

0 references

issue

2

0 references

page(s)

206-11

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Copy-number variations associated with neuropsychiatric conditions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

MeCP2, a key contributor to neurological disease, activates and represses transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Identification of MeCP2 mutations in a series of females with autistic disorder

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Nucleus accumbens μ-opioid receptors mediate social reward

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Up-regulation of the mu-opioid receptor gene is mediated through chromatin remodeling and transcriptional factors in differentiated neuronal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Autism and other neuropsychiatric symptoms are prevalent in individuals with MeCP2 duplication syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Morphological correlates of emotional and cognitive behaviour: insights from studies on inbred and outbred rodent strains and their crosses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Candidate genes of anxiety-related behavior in HAB/LAB rats and mice: focus on vasopressin and glyoxalase-I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

A method for automated detection of gene expression required for the establishment of a digital transcriptome-wide gene expression atlas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

A mutation hot spot for nonspecific X-linked mental retardation in the MECP2 gene causes the PPM-X syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Angelman syndrome phenotype associated with mutations in MECP2, a gene encoding a methyl CpG binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

De-novo 2.15 Mb terminal Xq duplication involving MECP2 but not L1CAM gene in a male patient with mental retardation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Increased MECP2 gene copy number as the result of genomic duplication in neurodevelopmentally delayed males.

2 June 2018

1 reference

Submicroscopic duplication in Xq28 causes increased expression of the MECP2 gene in a boy with severe mental retardation and features of Rett syndrome

21 January 2018

1 reference

Recurrent infections, hypotonia, and mental retardation caused by duplication of MECP2 and adjacent region in Xq28.

21 January 2018

1 reference

Two brothers with a microduplication including the MECP2 gene: rapid head growth in infancy and resolution of susceptibility to infection.

21 January 2018

1 reference

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

21 January 2018

1 reference

21 January 2018

2 references

21 January 2018

7 January 2021

inferred from DOI database lookup

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

1 reference

Effects of transgenic overproduction of CRH on anxiety-like behaviour

21 January 2018

1 reference

Deficit in attachment behavior in mice lacking the mu-opioid receptor gene

21 January 2018

1 reference

A direct approach to false discovery rates

21 January 2018

1 reference

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

21 January 2018

1 reference

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3267865

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need

27 November 2018

1 reference

Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22231481

12 December 2020

inferred from PubMed ID database lookup

Another patient with MECP2 mutation without classic Rett syndrome phenotype

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22231481

12 December 2020

inferred from PubMed ID database lookup

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor(1) receptor antagonist. II.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22231481

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.1066

1 reference

release_jwglsxhaazb27jpd47p7ht4ocy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jwglsxhaazb27jpd47p7ht4ocy

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

22231481

1 reference