(Q28257190)

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The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs

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The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs (English)

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Mindaugas Valius

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author name string

J P Montmayeur

1

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M Valius

2

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J Vandenheede

3

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A Kazlauskas

4

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language of work or name

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publication date

19 December 1997

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Journal of Biological Chemistry

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272

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51

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32670-8

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Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

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https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Receptor tyrosine kinases and their targets

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https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

1 reference

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21 January 2018

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

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21 January 2018

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

1 reference

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21 January 2018

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

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21 January 2018

Transcription mediated by a cAMP-responsive promoter element is reduced upon activation of dopamine D2 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

1 reference

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21 January 2018

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

1 reference

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21 January 2018

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

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21 January 2018

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Molecular cloning of gene sequences regulated by platelet-derived growth factor.

1 reference

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21 January 2018

Phosphorylation of tyrosine 720 in the platelet-derived growth factor alpha receptor is required for binding of Grb2 and SHP-2 but not for activation of Ras or cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

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https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Direct association of Grb2 with the p85 subunit of phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

SH2 domains recognize specific phosphopeptide sequences

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https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Proto-oncogene fos: complex but versatile regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.51.32670

21 January 2018

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10.1074/JBC.272.51.32670

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