(Q28257418)

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Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52

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scholarly article

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Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52 (English)

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Marie Wahren-Herlenius

7

object named as

Marie Wahren-Herlenius

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5

object named as

Vijay K Kuchroo

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author name string

Janosch Hennig

1

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Lars Ottosson

2

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Cecilia Andrésen

3

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Linn Horvath

4

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Klas Broo

6

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Maria Sunnerhagen

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language of work or name

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publication date

30 September 2005

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Journal of Biological Chemistry

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280

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33250-61

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39

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Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block

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Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

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MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation

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Leucine zipper domain of 52 kDa SS-A/Ro promotes protein dimer formation and inhibits in vitro transcription activity

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Ubiquitination of Ro52 autoantigen

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Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions

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Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression

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MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

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The ubiquitin system

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Self-assembly properties of a model RING domain

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Control of biochemical reactions through supramolecular RING domain self-assembly

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Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein

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Analysis of B-cell epitopes of the Ro/SS-A autoantigen

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Predicting coiled coils by use of pairwise residue correlations

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MultiCoil: a program for predicting two- and three-stranded coiled coils

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Identifiers

10.1074/JBC.M503066200

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