(Q28259619)

English

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF

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Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF (English)

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Jacques Pouysségur

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object named as

Jacques Pouysségur

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Darren E. Richard

object named as

Darren E Richard

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author name string

Rebecca Bilton

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Nathalie Mazure

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Eric Trottier

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Maurice Hattab

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Marc-André Déry

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M Christiane Brahimi-Horn

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language of work or name

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publication date

2 September 2005

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Journal of Biological Chemistry

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280

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31132-40

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35

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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

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Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

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Oxygen sensing by HIF hydroxylases

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Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications

1 reference

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

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Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

1 reference

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GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein.

1 reference

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis

1 reference

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Analysis of ARD1 function in hypoxia response using retroviral RNA interference

1 reference

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

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Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular endothelial growth factor mRNA.

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p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

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1 reference

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Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways

1 reference

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

1 reference

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Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

1 reference

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

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Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

1 reference

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

1 reference

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An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development

1 reference

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Identification and characterization of the human ARD1-NATH protein acetyltransferase complex

1 reference

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Tubedown-1 in remodeling of the developing vitreal vasculature in vivo and regulation of capillary outgrowth in vitro

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Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex

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NATH, a novel gene overexpressed in papillary thyroid carcinomas

1 reference

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Serological identification and expression analysis of gastric cancer-associated genes

1 reference

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The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways

1 reference

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Identifiers

10.1074/JBC.M504482200

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