(Q28260242)

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Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development

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Europe PubMed Central

Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development (English)

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atherosclerosis

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based on heuristic

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Miranda Van Eck

7

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Miranda Van Eck

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author name string

Marieke Pennings

1

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Illiana Meurs

2

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Dan Ye

3

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Ruud Out

4

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Menno Hoekstra

5

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Theo J C Van Berkel

6

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9 October 2006

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580

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23

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5588-96

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Atherosclerosis — An Inflammatory Disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

High affinity saturable uptake of oxidized low density lipoprotein by macrophages from mice lacking the scavenger receptor class A type I/II.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Scavenger receptors: friend or foe in atherosclerosis?

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Uptake of cholesterol-rich remnant lipoproteins by human monocyte-derived macrophages is mediated by low density lipoprotein receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The LDL receptor is the major pathway for beta-VLDL uptake by mouse peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Beyond endocytosis: LRP function in cell migration, proliferation and vascular permeability

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macrophage foam cell formation with native low density lipoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macropinosome maturation and fusion with tubular lysosomes in macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Localization of human ATP-binding cassette transporter 1 (ABC1) in normal and atherosclerotic tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ATP-binding cassette transporter G1 and lipid homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Evolution of ATP-binding cassette transporter genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The human ATP-binding cassette (ABC) transporter superfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Human ATP-binding cassette transporter TaqMan low-density array: analysis of macrophage differentiation and foam cell formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABCA6, a novel a subclass ABC transporter

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7)

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Potential role of ABCA7 in cellular lipid efflux to apoA-I

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Is the multidrug transporter a flippase?

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Opposite pattern of MDR1 and caveolin-1 gene expression in human atherosclerotic lesions and proliferating human smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Role of multidrug resistance P-glycoproteins in cholesterol esterification

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Multidrug resistance P-glycoprotein is not involved in cholesterol esterification.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Regulation of transbilayer plasma membrane phospholipid asymmetry

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Lipid traffic: floppy drives and a superhighway.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Natural phosphatidylcholine is actively translocated across the plasma membrane to the surface of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Tracking down lipid flippases and their biological functions.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Membrane lipids and vesicular traffic.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

How proteins move lipids and lipids move proteins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Incorporation of phospholipid analogues into the plasma membrane affects ATP-induced vesiculation of human erythrocyte ghosts.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Increased vesicle endocytosis due to an increase in the plasma membrane phosphatidylserine concentration

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Endocytosis is enhanced in Tangier fibroblasts: possible role of ATP-binding cassette protein A1 in endosomal vesicular transport

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Headgroup-specific exposure of phospholipids in ABCA1-expressing cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Flippases and vesicle-mediated protein transport

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Effective strategies for long-term statin use

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

Macropinocytosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2006.08.022

21 January 2018

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