(Q28266443)

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Therapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapy

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17014686%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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Europe PubMed Central

Therapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapy (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17014686%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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Paula A Witt-Enderby

1

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20 December 2019

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Nicholas M Radio

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20 December 2019

John S Doctor

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20 December 2019

Vicki L Davis

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20 December 2019

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1 November 2006

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20 December 2019

Journal of Pineal Research

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20 December 2019

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20 December 2019

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20 December 2019

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20 December 2019

Pharmacological characterization, molecular subtyping, and autoradiographic localization of putative melatonin receptors in uterine endometrium of estrous rats

1 reference

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21 April 2017

Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses

1 reference

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21 April 2017

Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor

1 reference

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21 April 2017

Allelic variants of human melatonin 1A receptor in patients with familial adolescent idiopathic scoliosis

1 reference

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21 April 2017

Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats

1 reference

https://api.crossref.org/works/10.1111/J.1600-079X.2006.00369.X

21 April 2017

Preventive and curative effect of melatonin on mammary carcinogenesis induced by dimethylbenz[a]anthracene in the female Sprague-Dawley rat

1 reference

https://api.crossref.org/works/10.1111/J.1600-079X.2006.00369.X

21 April 2017

MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1111/J.1600-079X.2006.00369.X

21 April 2017

Melatonin: reducing the toxicity and increasing the efficacy of drugs

1 reference

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21 April 2017

Human aging and melatonin. Clinical relevance.

1 reference

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21 January 2018

Expression of membrane and nuclear melatonin receptors in mouse peripheral organs.

1 reference

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21 January 2018

Therapeutic perspectives for melatonin agonists and antagonists.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Gastrointestinal melatonin: localization, function, and clinical relevance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Expression of membrane and nuclear melatonin receptor mRNA and protein in the mouse immune system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin, human aging, and age-related diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin receptor expression in rat cerebral artery

1 reference

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21 January 2018

Interactions between melatonin and estrogen may regulate cerebrovascular function in women: clinical implications for the effective use of HRT during menopause and aging

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

MT(2) melatonin receptors are present and functional in rat caudal artery

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Regulation of antioxidant enzymes: a significant role for melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin as a radioprotective agent: a review

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Functional melatonin receptors in rat ovaries at various stages of the estrous cycle

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Down-regulation of mt1 melatonin receptors in rat ovary following estrogen exposure.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Ocular hypotensive effects of melatonin receptor agonists in the rabbit: further evidence for an MT3 receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin effects on bone: experimental facts and clinical perspectives

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Mammalian cultured cells as a model system of peripheral circadian clocks

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Microarray technology in studying the effect of melatonin on gene expression in the mouse heart

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Transcriptional profiling of the chick pineal gland, a photoreceptive circadian oscillator and pacemaker

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Transcriptional profiling of circadian patterns of mRNA expression in the chick retina

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin receptors and their regulation: biochemical and structural mechanisms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin-estrogen interactions in breast cancer.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Identification of the melatonin-binding site MT3 as the quinone reductase 2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Metabolism and the control of circadian rhythms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Qualitative and quantitative changes of melatonin levels in physiological and pathological aging and in centenarians

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Skeletal disorders associated with skin pigmentation: a role of melatonin?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Changes in vascularity of cartilage endplate of degenerated intervertebral discs in response to melatonin administration in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Morphological, stereological and radiological changes in pinealectomized chicken cervical vertebrae.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Correlation between the age of pinealectomy and the development of scoliosis in chickens

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Pinealectomy induces malformation of the spine and reduces the mechanical strength of the vertebrae in Atlantic salmon, Salmo salar

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin signaling dysfunction in adolescent idiopathic scoliosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Bipedal ambulation induces experimental scoliosis in C57BL/6J mice with reduced plasma and pineal melatonin levels

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

The effect of pinealectomy on scoliosis development in young nonhuman primates

1 reference

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21 January 2018

The osteoblast: a sophisticated fibroblast under central surveillance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin suppresses osteoclastic and osteoblastic activities in the scales of goldfish.

1 reference

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21 January 2018

Melatonin at pharmacologic doses increases bone mass by suppressing resorption through down-regulation of the RANKL-mediated osteoclast formation and activation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin promotes osteoblast differentiation and bone formation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin increases oestradiol-induced bone formation in ovariectomized rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Evidence for a role of p38 MAP kinase in expression of alkaline phosphatase during osteoblastic cell differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

1-(5-oxohexyl)-3,7-Dimethylxanthine, a phosphodiesterase inhibitor, activates MAPK cascades and promotes osteoblast differentiation by a mechanism independent of PKA activation (pentoxifylline promotes osteoblast differentiation).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin deficiencies in women

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Night work and breast cancer risk: a systematic review and meta-analysis

1 reference

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21 January 2018

Melatonin and mammary pathological growth.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Serum melatonin circadian profiles in women suffering from cervical cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Circadian function in patients with advanced non-small-cell lung cancer

1 reference

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21 January 2018

A phase II study of tamoxifen plus melatonin in metastatic solid tumour patients

1 reference

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21 January 2018

Melatonin inhibits telomerase activity in the MCF-7 tumor cell line both in vivo and in vitro

1 reference

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21 January 2018

The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

N1E-115 mouse neuroblastoma cells express MT1 melatonin receptors and produce neurites in response to melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Differential expression of high-affinity melatonin receptors (MT1) in normal and malignant human breast tissue

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin slowed the early biochemical progression of hormone-refractory prostate cancer in a patient whose prostate tumor tissue expressed MT1 receptor subtype

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Overexpression of the MT1 melatonin receptor in MCF-7 human breast cancer cells inhibits mammary tumor formation in nude mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin decreases cell proliferation and transformation in a melatonin receptor-dependent manner

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

RNA expression of human telomerase subunits TR and TERT is differentially affected by melatonin receptor agonists in the MCF-7 tumor cell line

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin inhibits estrogen receptor transactivation and cAMP levels in breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: a molecular basis for melatonin-induced oncostatic effects.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial

1 reference

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21 January 2018

Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis

1 reference

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21 January 2018

Protective effect of melatonin against fractionated irradiation‐induced epiphyseal injury in a weanling rat model

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Seasonal rhythms of 6-sulphatoxymelatonin (aMT6s) excretion in female rats are abolished by growth of malignant tumors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2006.00369.X

21 January 2018

Daily coordination of cancer growth and circadian clock gene expression

1 reference

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21 January 2018

The therapeutic application of melatonin in supportive care and palliative medicine

1 reference

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21 January 2018

Identifiers

10.1111/J.1600-079X.2006.00369.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17014686%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17014686%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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