(Q28194026)

Rosa M Sainz

3

0 references

Russel J Reiter

1

Russel J Reiter

0 references

Dun-Xian Tan

2

Dun-Xian Tan

0 references

Silvia Lopez-Burillo

5

Journal of Pharmacy and Pharmacology

Silvia Lopez-Burillo

0 references

language of work or name

English

0 references

publication date

October 2002

0 references

published in

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volume

54

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issue

10

0 references

page(s)

1299-321

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cites work

Cell protective role of melatonin in the brain

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin, mitochondria, and cellular bioenergetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Protective effect of melatonin against adriamycin toxicity in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues of chick and their inhibition by light

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The effect of melatonin on bleomycin-induced pulmonary fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Gastric toxicity and mucosal ulceration induced by oxygen-derived reactive species: protection by melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects against gastric ulceration and increases the efficacy of ranitidine and omeprazole in reducing gastric damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin stimulates brain glutathione peroxidase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Nitrosation of melatonin by nitric oxide and peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Influence of melatonin upon the protective action of conventional anti-epileptic drugs against maximal electroshock in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Monozygotic twins with Alzheimer's disease treated with melatonin: Case report.

21 January 2018

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https://api.crossref.org/works/10.1211%2F002235702760345374

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Role of prostaglandins, nitric oxide, sensory nerves and gastrin in acceleration of ulcer healing by melatonin and its precursor, L-tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Localization, physiological significance and possible clinical implication of gastrointestinal melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects neurons from singlet oxygen-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin for treatment of sundowning in elderly persons with dementia - a preliminary study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Evidence for melatonin synthesis in mouse and human bone marrow cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Identification of the factors affecting the rate of deactivation of hypochlorous acid by melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin and the circadian regulation of sleep initiation, consolidation, structure, and the sleep EEG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin in epilepsy: first results of replacement therapy and first clinical results.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects of melatonin on the proliferation and cis-diamminedichloroplatinum (CDDP) sensitivity of cultured human ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Improvement of sleep quality in elderly people by controlled-release melatonin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin is a scavenger of peroxynitrite

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects of melatonin treatment in septic newborns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects of melatonin on doxorubicin cytotoxicity in sensitive and pleiotropically resistant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

A brief survey of pineal gland-immune system interrelationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin-immune system relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Nuclear receptors are involved in the enhanced IL-6 production by melatonin in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin, a pineal secretory product with antioxidant properties, protects against cisplatin-induced nephrotoxicity in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The significance of the metabolism of the neurohormone melatonin: antioxidative protection and formation of bioactive substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

On the primary functions of melatonin in evolution: mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Induction of DNA crosslinks and DNA strand lesions by cyclophosphamide after activation by cytochrome P450 2B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin prevents oxidative stress resulting from iron and erythropoietin administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Clinical trials of controlled-release melatonin in children with sleep-wake cycle disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Presence of a distinct 24-hour melatonin rhythm in the ventricular cerebrospinal fluid of the goat

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Free radicals and the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin increases gene expression for antioxidant enzymes in rat brain cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Is there a role for melatonin in supportive care?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Chemoneuroendocrine therapy of metastatic breast cancer with persistent thrombocytopenia with weekly low-dose epirubicin plus melatonin: a phase II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Thrombopoietic properties of 5-methoxytryptamine plus melatonin versus melatonin alone in the treatment of cancer-related thrombocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin and other antioxidants prolong the postmortem activity of the outer hair cells of the organ of Corti: its relation to the type of death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Ototoxicity caused by cisplatin is ameliorated by melatonin and other antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Poor response to treatment of renal anaemia with erythropoietin corrected by iron given intravenously

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The immunotherapeutic potential of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

A unifying hypothesis for the mechanism of NSAID related gastrointestinal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Evaluation of the antioxidant activity of melatonin in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Maternal pinealectomy abolishes the diurnal rhythm in plasma melatonin concentrations in the fetal sheep and pregnant ewe during late gestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Distribution of melatonin in mammalian tissues: the relative importance of nuclear versus cytosolic localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Utility of high doses of melatonin as adjunctive anticonvulsant therapy in a child with severe myoclonic epilepsy: two years' experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin, a pineal hormone with antioxidant property, protects against adriamycin cardiomyopathy in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Zinc accumulation in adriamycin-induced cardiomyopathy in rats: effects of melatonin, a cardioprotective antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin's role as an anticonvulsant and neuronal protector: experimental and clinical evidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin and its precursors scavenge nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin stimulates glutathione peroxidase activity in human chorion

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The protective action of melatonin on indomethacin-induced gastric and testicular oxidative stress in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin administration prevents the nephrotoxicity induced by gentamicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects of melatonin, morphine and diazepam on formalin-induced nociception in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin: a peroxyl radical scavenger more effective than vitamin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin-A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitroa

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Mechanism of cisplatin ototoxicity: antioxidant system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The Pineal and Its Hormones in the Control of Reproduction in Mammals*

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

A review of the evidence supporting melatonin's role as an antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin receptors: molecular biology of a new family of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Mechanism of Protection by Diethyldithiocarbamate against Cisplatin Ototoxicity: Antioxidant System

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Polyunsaturated fatty acids, melatonin, and cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects against gentamicin-induced nephrotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin treatment for tardive dyskinesia: a double-blind, placebo-controlled, crossover study

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Gene expression of the key enzymes of melatonin synthesis in extrapineal tissues of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

High physiological levels of melatonin in the bile of mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Significance of melatonin in antioxidative defense system: reactions and products

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects of long-term, low-dose, time-specified melatonin administration on endocrine and cardiovascular variables in adult men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects human red blood cells from oxidative hemolysis: new insights into the radical-scavenging activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin enters the cerebrospinal fluid through the pineal recess

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Nitrosation of melatonin by nitric oxide: a computational study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin in plant organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects fetal rat brain against oxidative mitochondrial damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Evidence suggesting a role for hydroxyl radical in gentamicin-induced acute renal failure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

The effects of exogenous melatonin on endocrine function in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effects by doxorubicin on the myocardium are mediated by oxygen free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin protects against cardiac toxicity of doxorubicin in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Preventive effect of melatonin against cyanide-induced seizures and lipid peroxidation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Melatonin attenuates L-cysteine-induced seizures and lipid peroxidation in the brain of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Effect of melatonin, piperonyl butoxide, or cobalt chloride on L-cysteine-induced lipid peroxidation in homogenate from whole brain of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374

Biochemistry of Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F002235702760345374