(Q34335212)

1 August 2017

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title

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis (English)

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1 August 2017

0 references

2

Reiter RJ

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1 August 2017

Poeggeler B

1

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1 August 2017

Tan DX

series ordinal

3

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1 August 2017

Chen LD

series ordinal

4

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1 August 2017

Manchester LC

series ordinal

5

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1 August 2017

publication date

1 May 1993

1 reference

Journal of Pineal Research

1 August 2017

published in

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1 August 2017

volume

14

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1 August 2017

issue

4

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1 August 2017

page(s)

151-168

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Brain weight and life-span in primate species

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Effect of pineal peptide preparation (epithalamin) on life span and pineal and serum melatonin level in old rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Melatonin in human cerebrospinal fluid in daytime; Its origin and variation with age

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Peroxidative block of glucose utilization and survival in CNS neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Protection of DNA damage by dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Excitatory Amino Acid Receptors may Mediate the Effects of Light on the Reproductive System of the Golden Hamster1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Peroxide-producing potential of tissues: inverse correlation with longevity of mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Kainic acid-induced seizures in aged rats: neurochemical correlates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Glutamate accumulation and increased hydroxyl free radical formation in the abdominal aorta and heart of gerbil after ischemia/reperfusion insult

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Mg2+ antagonizes alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced brain damage and convulsions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Carcinogen-mediated oxidant formation and oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

The inhibition of pineal arylalkylamine n-acetyltransferase by glutamic acid and its analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Reactive oxygen species and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Biologically relevant metal ion-dependent hydroxyl radical generation. An update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Calcium-dependent mitochondrial oxidative damage promoted by 5-aminolevulinic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Effect of tryptophan administration on circulating melatonin levels in chicks and rats: evidence for stimulation of melatonin synthesis and release in the gastrointestinal tract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Down's syndrome: a pathology involving the lack of balance of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Chronically elevating plasma Mg2+ improves hippocampal frequency potentiation and reversal learning in aged and young rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Possible Pineal-Suprachiasmatic Clock Regulation of Development and Life Span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Effect of noncompetitive blockade of N-methyl-D-aspartate receptors on the neurochemical sequelae of experimental brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

The effects of glutamate on membrane potential and discharge rate of suprachiasmatic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Aging: hypothalamic catecholamines, neuroendocrine-immune interactions, and dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Favorable effects of the antioxidants sodium and magnesium thiazolidine carboxylate on the vitality and life span of Drosophila and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Effect of magnesium hydroxide on methylazoxymethanol acetate-induced epithelial proliferation in the large bowels of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Melatonin modifies the spontaneous multiunit activity recorded in several brain nuclei of freely behaving rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Distribution and stress-induced increase of glutamate and aspartate levels in discrete brain nuclei of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

The osmotic/calcium stress theory of brain damage: are free radicals involved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Mechanisms of drug actions against neuronal damage caused by ischemia--an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Prevention by Ginkgo biloba extract (EGb 761) and trolox C of the decrease in synaptosomal dopamine or serotonin uptake following incubation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Melatonin: the chemical expression of darkness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Neuroendocrine effects of light

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

The ageing pineal gland and its physiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

The role of glutathione in aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Pituitary-adrenocortical and pineal activities in the aged rat. Effects of long-term treatment with acetyl-L-carnitine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Protein oxidation in aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

N-Methyl-d-aspartate, quisqualate and kainate receptors are all involved in transmission of photic stimulation in the suprachiasmatic nucleus in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Alzheimer skin fibroblasts show increased susceptibility to free radicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Concentrations of serotonin and its related substances in the cerebrospinal fluid in patients with Alzheimer type dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Magnesium sulphate subcutaneously injected protects against kainate-induced convulsions and neurodegeneration: In vivo study on the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Subcutaneously applied magnesium protects reliably against quinolinate-induced N-methyl-D-aspartate (NMDA)-mediated neurodegeneration and convulsions in rats: are there therapeutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Basal forebrain cholinergic neurons in aged rat brain are more susceptible to ibotenate-induced degeneration than neurons in young adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

Evidence that the loss of the voltage-dependent Mg2+ block at the N-methyl-D-aspartate receptor underlies receptor activation during inhibition of neuronal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

A proposal for reconsideration of the role of oxygen free radicals in cell differentiation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.1993.TB00498.X

10.1111/J.1600-079X.1993.TB00498.X

21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference