(Q28266893)

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Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis

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scholarly article

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Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis (English)

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carbapenem antibiotic

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(5S)-5-(carboxymethyl)-L-proline(1-)

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ChEBI release 2020-05-28

(5S)-5-(carboxymethyl)-L-proline

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ChEBI release 2020-05-28

Christopher J. Schofield

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Michael A McDonough

object named as

Michael A McDonough

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author name string

Mark C Sleeman

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John L Sorensen

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Edward T Batchelar

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language of work or name

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publication date

14 October 2005

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Journal of Biological Chemistry

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280

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41

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34956-65

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Proteins of the penicillin biosynthesis pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507196200

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Chemistry and biosynthesis of clavulanic acid and other clavams

1 reference

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Biosynthesis and molecular genetics of clavulanic acid

1 reference

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New reactions in clavulanic acid biosynthesis

1 reference

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beta-Lactam synthetase: a new biosynthetic enzyme

1 reference

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Inhibition and alternate substrate studies on the mechanism of carbapenam synthetase from Erwinia carotovora

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Analysis of bacterial carbapenem antibiotic production genes reveals a novel β-lactam biosynthesis pathway.

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Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterization

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Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus

1 reference

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21 January 2018

Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis

1 reference

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21 January 2018

Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily

1 reference

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21 January 2018

The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters

1 reference

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Divergent Function in the Crotonase Superfamily: An Anhydride Intermediate in the Reaction Catalyzed by 3-Hydroxyisobutyryl-CoA Hydrolase

1 reference

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21 January 2018

A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization

1 reference

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The CCP4 suite: programs for protein crystallography

1 reference

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A high-throughput structural biology/proteomics beamline at the SRS on a new multipole wiggler.

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

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Maximum-likelihood density modification

1 reference

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Coot: model-building tools for molecular graphics

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507196200

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Likelihood-enhanced fast translation functions

1 reference

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Likelihood-enhanced fast rotation functions

1 reference

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Improved protein-ligand docking using GOLD

1 reference

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

1 reference

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21 January 2018

Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis

1 reference

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21 January 2018

Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 A resolution: an enzyme catalyst generated via adaptive mutation

1 reference

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The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

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21 January 2018

Detection, delineation, measurement and display of cavities in macromolecular structures

1 reference

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21 January 2018

Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase

1 reference

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21 January 2018

The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase

1 reference

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21 January 2018

New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli

1 reference

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The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily

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Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis

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The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule

1 reference

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21 January 2018

Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).

1 reference

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21 January 2018

Genetic approaches to polyketide antibiotics. 1.

1 reference

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Rules for ring closure

1 reference

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21 January 2018

Structural studies on Δ3-Δ2-enoyl-CoA isomerase: the variable mode of assembly of the trimeric disks of the crotonase superfamily

1 reference

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21 January 2018

Origin of the β-Lactam Carbons in Clavulanic Acid from an Unusual Thiamine Pyrophosphate-Mediated Reaction

1 reference

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21 January 2018

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10.1074/JBC.M507196200

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