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Resistance to therapy caused by intragenic deletion in BRCA2
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scholarly article
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title
Resistance to therapy caused by intragenic deletion in BRCA2
(English)
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author
Rachael Natrajan
series ordinal
4
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Alan Ashworth
series ordinal
9
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Jorge Reis-Filho
series ordinal
8
object named as
Jorge S Reis-Filho
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Christopher J Lord
object named as
Christopher J Lord
series ordinal
3
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Rachel Brough
series ordinal
2
object named as
Rachel Brough
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Radost Vatcheva
series ordinal
5
object named as
Radost Vatcheva
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author name string
Stacey L Edwards
series ordinal
1
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Douglas A Levine
series ordinal
6
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Jeff Boyd
series ordinal
7
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language of work or name
English
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publication date
28 February 2008
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published in
Nature
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volume
451
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page(s)
1111-5
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issue
7182
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cites work
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRCA2 is required for homology-directed repair of chromosomal breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical management of BRCA1 and BRCA2 mutation carriers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRCA2 regulates homologous recombination in response to DNA damage: implications for genome stability and carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved survival in women with BRCA-associated ovarian carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved survival in BRCA2 carriers with ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular processing of platinum anticancer drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo reversion to normal of inherited mutations in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sulforhodamine B colorimetric assay for cytotoxicity screening.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calculating slope and ED50 of additive dose-response curves, and application of these tabulated parameter values.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE06548
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NATURE06548
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3006478
Dimensions Publication ID
1040539424
0 references
OpenCitations bibliographic resource ID
3006478
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3006478
PubMed ID
18264088
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3006478
Springer Nature article ID
10.1038/nature06548
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