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PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)

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PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1) (English)

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Eun-Jung Suh

1

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Tae-Yoon Kim

series ordinal

2

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Sang Hoon Kim

series ordinal

3

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language of work or name

English

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publication date

13 November 2006

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published in

FEBS Letters

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volume

580

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issue

26

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page(s)

6100-4

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cites work

Role of serine/threonine protein phosphatase 2A in cancer

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Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C alpha and beta 2 isoforms

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The structure and regulation of protein phosphatases

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21 January 2018

Cloning and characterization of a novel mammalian PP2C isozyme

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Molecular cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*).

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21 January 2018

Dephosphorylation of cyclin-dependent kinases by type 2C protein phosphatases

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Thr-161 phosphorylation of monomeric Cdc2. Regulation by protein phosphatase 2C in Xenopus oocytes

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Protein dephosphorylation and the intracellular control of the cell number.

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Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle

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The type 2C Ser/Thr phosphatase PP2Cgamma is a pre-mRNA splicing factor

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N-acetylation and ubiquitin-independent proteasomal degradation of p21(Cip1).

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Decreased p21 levels are required for efficient restart of DNA synthesis after S phase block

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A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

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Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

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Regulation of the cell cycle by SCF-type ubiquitin ligases

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Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

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Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.

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Identifiers

DOI

10.1016/J.FEBSLET.2006.10.005

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PubMed ID

17054950

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ResearchGate publication ID

6740844

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(Q28269770)

PP2Cgamma-mediated S-phase accumulation induced by the proteasome-dependent degradation of p21(WAF1/CIP1)

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