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Oral renin inhibitors
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scholarly article
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review article
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Europe PubMed Central
title
Oral renin inhibitors
(English)
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author
Jan A. Staessen
object named as
Jan A Staessen
series ordinal
1
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Yan Li
series ordinal
2
object named as
Yan Li
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author name string
Tom Richart
series ordinal
3
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language of work or name
English
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publication date
21 October 2006
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published in
The Lancet
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volume
368
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issue
9545
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page(s)
1449-56
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cites work
Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases
1 reference
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Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents
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reference URL
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7 January 2021
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Intermediate but not low doses of aspirin can suppress angiotensin-converting enzyme inhibitor-induced cough
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Plasma bradykinin in angio-oedema.
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Renin inhibition: what are the therapeutic opportunities?
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7 January 2021
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Pharmacology of renin inhibitors and their application to the treatment of hypertension
1 reference
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reference URL
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7 January 2021
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Pathways for angiotensin II generation in intact human tissue: evidence from comparative pharmacological interruption of the renin system
1 reference
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reference URL
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The preparation, purification, and amino acid sequence of a polypeptide renin substrate
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Antibodies to renin as proof of the pathogenesis of sustained renal hypertension
1 reference
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7 January 2021
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PRODUCTION OF ANTIRENIN TO HOMOLOGOUS RENIN AND ITS EFFECT OF EXPERIMENTAL RENAL HYPERTENSION
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7 January 2021
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Active immunization against renin in normotensive marmoset
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reference URL
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7 January 2021
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inferred from DOI database lookup
Inhibition of the renin-angiotensinogen reaction by pepstatin
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7 January 2021
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Analysis of structure-activity relationships in renin substrate analogue inhibitory peptides.
1 reference
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7 January 2021
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Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine
1 reference
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reference URL
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7 January 2021
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Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond
1 reference
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Crossref
reference URL
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7 January 2021
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A study of the renin inhibitor H142 in man
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7 January 2021
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Effects of a specific and long-acting renin inhibitor in the marmoset
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Pharmacological investigations of a new renin inhibitor in normal sodium-unrestricted volunteers
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Clinical Pharmacokinetics and Efficacy of Renin Inhibitors
1 reference
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reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hemodynamics, biochemical effects, and pharmacokinetics of the renin inhibitor remikiren in healthy human subjects
1 reference
stated in
Crossref
reference URL
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inferred from DOI database lookup
Dose-Dependent Effects of the Renin Inhibitor Zankiren HCl After a Single Oral Dose in Mildly Sodium-Depleted Normotensive Subjects
1 reference
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Piperidine renin inhibitors: from leads to drug candidates
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7 January 2021
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Direct micro-radioimmunoassay of the new renin inhibitor CGP 60536.
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7 January 2021
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Structure-based design of aliskiren, a novel orally effective renin inhibitor
1 reference
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7 January 2021
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Comparative effects of three different potent renin inhibitors in primates
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7 January 2021
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Ro 42-5892 is a potent orally active renin inhibitor in primates
1 reference
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7 January 2021
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inferred from DOI database lookup
Effects of chronic infusion of renin inhibitor A-64662 in sodium-depleted monkeys
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7 January 2021
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New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon
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Crossref
reference URL
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7 January 2021
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Renal and endocrine responses to a renin inhibitor, enalkiren, in normal humans
1 reference
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7 January 2021
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Hemodynamic and humoral effects of the new renin inhibitor enalkiren in normal humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Responses to an orally active renin inhibitor, remikiren (Ro 42-5892), after controlled salt depletion in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Renal vascular responses to renin inhibition with zankiren in men*
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
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inferred from DOI database lookup
Effect of the renin response during renin inhibition: oral Ro 42-5892 in normal humans
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
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inferred from DOI database lookup
Effects of an orally active renin inhibitor, Ro 42-5892, in patients with essential hypertension.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and tolerability of the renin inhibitor Ro 42-5892 in patients with hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Renal and systemic effects of the renin inhibitor remikiren in patients with essential hypertension
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Plasma angiotensins, renin, and blood pressure during acute renin inhibition by CGP 38 560A in hypertensive patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of the renin inhibitor A-64662 in monkeys and rats with varying baseline plasma renin activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue renin-angiotensin systems and reproduction
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Renin inhibitor and converting enzyme inhibitors suppress vascular angiotensin II
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Major role of the renin angiotensin system in the neointima formation after vascular injury in guinea pigs
1 reference
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https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
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Carotid Intima-Media Thickness and Antihypertensive Treatment
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Renal vascular and biochemical responses to systemic renin inhibition in dogs at low renal perfusion pressure
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of blocking the angiotensin II receptor, converting enzyme, and renin activity on the renal hemodynamics of normotensive guinea pigs.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Responses to converting enzyme and renin inhibition. Role of angiotensin II in humans
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Renal and systemic effects of continued treatment with renin inhibitor remikiren in hypertensive patients with normal and impaired renal function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hemodynamic Effects of Angiotensin and Renin Inhibition in Dogs with Acute Left Ventricular Failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of angiotensin converting enzyme and renin inhibition in rats following myocardial infarction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative effects of three sites of renin-angiotensin blockade on the regression of left ventricular hypertrophy in spontaneously hypertensive rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiotensinergic versus nonangiotensinergic hemodynamic effects of converting enzyme inhibition in patients with chronic heart failure. Assessment by acute renin and converting enzyme inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hemodynamic effects of renin inhibition by enalkiren in chronic congestive heart failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of the oral renin inhibitor aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in healthy subjects
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blood pressure reduction and cardiovascular prevention: an update including the 2003-2004 secondary prevention trials
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
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Systolic and diastolic blood pressure lowering as determinants of cardiovascular outcome
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of valsartan and perindopril combination therapy on left ventricular hypertrophy and aortic arterial stiffness in patients with essential hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0140-6736%2806%2969442-7
retrieved
7 January 2021
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Identifiers
DOI
10.1016/S0140-6736(06)69442-7
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PubMed publication ID
17055947
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